<p><strong>Background: </strong>Neonatal sepsis is a major cause of neonatal mortality and morbidity throughout the world. Though blood culture is the gold standard and has higher sensitivity and specificity over the hematological value and cytokine, it is not available in our community health situation and also in most of health care facilities. It is also time consuming. Therefore hematological value and interleukin-6 can be evaluated for the early diagnosis of neonatal bacterial infection.</p> <p><strong>Objective: </strong>This study was conducted to see the usefulness of IL-6 as an early marker of neonatal sepsis and also to compare the sensitivity in comparison with CRP, hematological value and blood culture.</p> <p><strong>Study Design: </strong>It was a quasy experimental study.</p> <p><strong>Setting: </strong>This study was carried out in the neonatal unit of pediatric department, BSMMU during the period of September, 2005 to February, 2006.</p> <p><strong>Method: </strong>Forty five suspected septic cases were enrolled in the study and thirty healthy newborn were taken for comparison. Venous blood sample from peripheral vein was collected on the 1st day of symptoms and/or 1st day of admission and was sent for IL-6 estimation within half an hour and estimation of IL-6 was done by using immunolyte DPC USA which employed automated chemiluminescent immunoassays.</p> <p><strong>Results: </strong>Out of forty five cases of suspected-neonatal sepsis, IL-6 were positive in twenty five cases. In culture proven sepsis 100% cases had raised IL-6. In control group only five babies had raised IL-6. Three cases were culture positive, of which all were also positive for IL-6 (100%). Among the cases twenty six were CRP positive, of which twenty were also positive for IL-6 (76.92%).</p> <p><strong>Conclusion: </strong>In the present study IL-6 was found to be an early marker of neonatal infection. Sensitivity was more than CRP and other hematological parameter in the first twenty four hours.</p> <p><strong>Key words: </strong>Interleukin-6, Neonatal Sepsis.</p><p>DOI: 10.3329/bsmmuj.v1i1.3687</p> <p><em>BSMMU J </em>2008; 1(1): 1-5</p>

doi: 10.3329/jcmcta.v18i2.3826Journal of Chittagong Medical College Teachers' Association 2007: 18(2):21-25

Kartagener's syndrome or primary ciliary dyskinesia (PCD) is a very rare congenital malformation comprising of a classic triad of sinusitis, situs inversus, and bronchiectasis. PCD is a genetic disorder with manifestations present from early life, and this distinguishes it from acquired mucociliary disorders. Approximately one half of patients with PCD have situs inversus. We present a case of 12-year-old girl with sinusitis, situs inversus, and bronchiectasis. The correct diagnosis of this rare congenital autosomal recessive disorder in early life is important for the overall prognosis of the syndrome, as many of the complications can be prevented if timely management is instituted.

Miliary tuberculosis is a form of disseminated tuberculosis, which is more frequent in immunocompromised patient. Ocular involvement of mycobacterium tuberculosis is also an uncommon presentation of disseminated tuberculosis. Tubercular uveitis is most frequent form of ocular tuberculosis. If treatment is delayed, it may cause loss of vision. In many case of the systemic TB with ocular involvement, there may be no eye symptoms in early stage. On the other hand, many cases of ocular TB may not have any evidence of systemic TB. Here we have described a case of miliary tuberculosis with ocular uveitis who initially presented with fever without any significant physical findings and later developed eye symptoms including diminished vision. Bangladesh J Child Health 2019; VOL 43 (2) :126-130

DOI: 10.3329/bjch.v33i3.5692Bangladesh Journal of Child Health 2009; Vol.33(3): 111-113