Introduction Organization survival is dependent on communications and managers spend a main portion of their time to establish communications. The identification, improvement and development of communication skills serve as the essential components of successful organizations. The present study aimed to investigate the role of communication skills in human resource productivity in north Iran.Method The study employed a cross-sectional design and was conducted in six deputies supervised by the Alborz University of Medical Sciences, in 2019. The statistical population included all 302 employees were selected as the sample population according to Cochran's formula. Using two researcher-made questionnaires of communication skills and human resource productivity, we assessed the role of communication skills in human resource productivity. Data were analyzed by implementing descriptive statistics including mean and standard deviation (SD), and analytical statistics such as Kolmogorov‐Smirnov, ANOVA, Pearson correlation coefficient, T-test and multivariate regression tests using SPSS 21 and P ≤ 0.05.Results According to research findings, there were significant relationships between communication skills including verbal skills, listening skills and effectiveness skills with human resource productivity P ≤ 0.05. There was a significant relationship between age group, gender, level of education and travel home-university distance with communication skills and resource productivity of employees P ≤ 0.05.Conclusion This study examines the role of communication skills in the promotion of human resource productivity who work in the administrative section of the University of Medical Sciences in Iran. Findings suggest that health planners and authorities may need to examine factors that contribute to the promotion of the communication skills for increase human resource productivity of employees and improved performance of health organizations.