No abstract

Microbial lipases owing to their broad substrate specificity are widely used in various industrial applications like food processing, organic synthesis, detergent formulation and oil manufacturing. In the current study the immobilized lipase from Lactobacillus plantarum was found novel in degrading meat which can be applied in medical field and also in synthesizing different short chain fatty acid esters like 2,3,4-hydroxybenzyl acetates and triazole ester which makes a great impingement in natural flavor industry. The 4-hydroxybenzyl acetate obtained can also be used in cosmetics.

No abstract

The bipyridine‐based constructs 4‐(pyridine‐2‐yl)‐3H‐pyrrolo[2,3‐c]quinoline (PPQ) and [6‐(3H‐pyrrolo[2,3‐c]quinolin‐4‐yl)pyridin‐2‐yl]methanol (PPQ‐OH) and their assemblies with surfactants are evaluated as turn‐on fluorescent sensors for Zn2+ ions in aqueous solution. This study strives to overcome the problem of low water solubility of the hydrophobic PPQ and PPQ‐OH by using micelles. Whereas the ligands show selective sensing behavior for Zn2+ over important biological cations including Na+, K+, Ca2+, Mg2+ in anionic sodium dodecyl sulfate and non‐ionic Tween 80 micelles, no Zn2+ sensing is observed in cationic cetyltrimethylammonium bromide micelles. Unlike in DMF, Cd2+ interference is observed in aqueous conditions, which can be avoided either by performing the study at pH≥9 or by carrying out a time‐resolved fluorescence study. Analysis of the Job plot data, the fluorescence lifetimes, and experiments on varying micellar shape and pH, confirms that the coordination volume of the resulting octahedral metal complex and formation of a five‐membered chelate ring are critical factors for Cd2+ interference. The described sensing systems are capable of detecting Zn2+ ions at the micromolar level. Additionally, it is shown that PPQ and PPQ‐OH can be used to detect Zn2+ in HeLa cells under physiological conditions in bioimaging studies.

Simple two step synthesis of fused thieno-/furo-quinoline (or [1,8]-naphthyridine) compounds by sequential application of Suzuki coupling and modified Pictet–Spengler synthesis.