Key WordsNasopharyngeal Angiofibroma, pre-operative embolization.
MATERIALS AND METHODSNine cases of proved nasopharyngeal angiofibroma after clinical evaluation, imaging and angiography, were subjected for the surgical resection.First four cases of Stage I and II were approached by transpalatal route and whole tumour mass with pedicle attached at the nasopharynx was excised. These cases which did not undergo embolization and the total blood loss of 10-12 units was quite significant intra-operatively.The second group of three cases of stage II B and C were subjected for surgical clearance by lateral rhinotomy and transpalatal approach. The whole mass could be removed. The preoperative embolization reduced intra operative blood loss considerably to 2 units only post operative recovery was uneventful. The third group of Fig-I
C. T. 5can ~f patient with An qiofibrtmla
Acute invasive fungal sinusitis is a significant cause of morbidity and mortality especially in immunocompromised patients. The offending organism usually belongs to the classes Zygomycetes (Mucorspp) and Ascomycetes (Aspergillus spp). However, in the last few decades, Pseudallescheria boydii (P.boydii) has been emerging as an important human pathogen, particularly in immunocompromised hosts.[1] Although P boydii resembles Aspergillus on pathologic examination, it is crucial to identify it as it is typically resistant to amphotericin B. Patients with P boydii sinusitis should generally be treated with a combination of surgery and antifungal therapy. This is particularly important in immunocompromised patients with fungal invasion because mortality among these patients is high.Our case report highlights the importance of distinguishing P. boydii from Aspergillus in a diabetic patient with invasive fungal sinusitis to prevent irreversible complications of the disease along with a review of literature of similar cases.
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