Introduction and Aim: Polycystic Ovarian Syndrome (PCOS) manifests with menstrual irregularities, infertility, galactorrhoea and hirsutism. Hormonal irregularities are found to be the pathogenesis behind PCOS. The study was aimed to evaluate whether obesity is associated with serum prolactin and insulin levels in PCOS women.    Materials and Methods: This case control study was conducted in a tertiary care hospital in Chennai. Control group included 30 apparently healthy women and cases included 30 PCOS patients, diagnosis based on Rotterdam criteria. The individuals were of 20-40 years of age in both the groups. The serum prolactin and insulin were analysed by ELISA. The obtained data were checked for normality of distribution and subjected to statistical analysis. Receiver Operating Characteristics (ROC) curve was done. Statistical analyses were performed using SPSS version 16.0. P less than 0.05 was considered statistically significant.   Results: The median and interquartile range (IQR) of serum insulin were 11.5 (1.8-70) and 5 (1.8-44) mIU/L in cases and controls respectively. The cut-off level of insulin was 7.0 mIU/L. The median and IQR of serum prolactin were 12.5 (4.5-53.0) and 12 (3.5-20) ng/mL in cases and controls respectively. BMI was positively correlated with age of the participants and prolactin.   Conclusion: PCOS is prevalent among obese reproductive individuals. Insulin was markedly elevated in PCOS individuals. Insulin resistance alters levels of luteinizing hormone and sex hormone binging globulins. Hyperprolactinemia is associated with anovulation or oligoovulation, galactorrhoea and hirsutism. In obese PCOS women, prolactin and insulin could be diagnostic markers of PCOS.

Introduction and Aim: The COVID-19 pandemic has caused a huge economic burden and impacted physical and mental health of the people. The young medical graduates are facing a lot of disappointments with regard to career, higher studies, personal life etc. The current research aims to assess the various stressors and their coping strategies among the young medical graduates during the COVID-19 pandemic. Materials and Methods: The cross-sectional study was conducted in the Department of General Medicine at a tertiary care teaching hospital in South India. Undergraduate medical students of 228 in number of both genders who completed their residency training just before and during the COVID-19 pandemic were enrolled in the study. The data was collected through a preformed questionnaire. Ethics clearance was obtained from the Institutional Ethics Committee. Informed consent was obtained. Statistical analysis was done by SPSS software version 18.0. P value < 0.05 was considered statically significant. Results: The mean scores obtained in PSS-10 were found to be higher among males than females. Around 79.4% showed moderate stress while 20.6% showed high stress (P=0.001). Males showed more stress compared to females in general as well as academic stressors. Male doctors and female doctors had differing stress coping skills. Conclusion: The study highlighted the vulnerable state of mind of the young medical doctors. The best way to overcome stress is by providing adequate resources, training to cope stress and ambient conditions for study and work, social support and relaxation techniques at both individual and organisational levels to help them to achieve a reasonable work-family interface.