It is important to protect assets located within cavities vulnerable to incident shock waves generated by explosions. The aim of the present work is to explore if closed cell aluminum foams can mediate and attenuate incident shocks experienced by cavities. A small cavity of 9 mm diameter and 2 mm length was created within the steel end-wall of a shock tube and exposed to shocks, directly or after isolating by aluminum foam liners. Shock waves with incident pressure of 9–10 bar travelling at a velocity of 1000–1050 m/s were generated in the shock tube. Compared to the no-foam condition, the pressure induced in the cavity was either equal or lower, depending on whether the foam density was low (0.28 g/cc) or high (0.31 to 0.49 g/cc), respectively. Moreover, the rate of pressure rise, which was very high without and with the low density foam barrier, reduced substantially with increasing foam density. Foams deformed plastically under shock loading, with the extent of deformation decreasing with increasing foam density. Some interesting responses such as perforation of cell walls in the front side and densification in the far side of the foam were observed by a combination of scanning electron microscopy and X-ray microscopy. The present work conclusively shows that shocks in cavities within rigid walls can be attenuated by using foam liners of sufficiently high densities, which resist densification and extrusion into the cavities. Even such relatively high-density foams would be much lighter than fully dense materials capable of protecting cavities from shocks.
Ethanolic extract aerial portions of Coriandrum sativum (EECS) were tested for their anxiolytic eff ects on the cold-resistant stress test after seven days of treatment and their cognitive boosting eff ects after eight days of therapy (EECS). Total phenolic content and fl avonoid compound levels were calculated. C. sativum showed anti-stress effi cacy in a cold-resistant stress animal at 200 and 400 mg/kg doses. The plasma glucose, triglyceride, cholesterol levels, as well as the weight of the adrenal glands are all aff ected by the stimulation of the HPA in stressful situations. Pre-treatment with EECS and Geriforte, which contain secondary metabolites such as fl avonoids, glycosides, triterpenoids, and phenolic compounds, signifi cantly reduced stress-induced changes in these biochemical levels in cold stress animals. Screening for acetylcholinesterase inhibition activity in-vitro using Ellman’s approach increased AChE inhibition dose-dependently in the brains of mice. The data proved that the extract’s potential to reduce pain in-vitro is what led to the observed cognitive benefi ts in-vivo. Animals given EECS at 200 and 400 mg/kg had their infl exion ratio improved as a result of the memory defi cit being reversed. The scopolamine-induced amnesia group of mice showed degeneration of vacuolated cells, pyramidal cells, pyknosis, loss of architecture and the creation of lesions in the hippocampus; however, these characteristics were restored by EECS and standard therapy. Eff ective docking scores in mcule software were observed for interactions with receptors PDB: 4K5Y (CRF-1) for adaptogenic and PDB: 1E66 (AChE) for cognition, according to in-silico research. The ethanolic extract of C. sativum has been shown to have positive and scientifi cally-supported eff ects on human health when used as a nutraceutical, with the in-vitro acetylcholinesterase Inhibition assay, anti-stress, and cognitive enhancement activities, and in-silico studies all corroborated by this study.
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