Vascularity is a highly essential element that is required for the growth, development, and functioning of the body and variations in it can cause pathologies. It is one of the prime features of a proliferating lesion, where it aids in the growth of the lesion through its nutrition supply. Highly increased vascularity in a disease can itself affect the prognosis of the lesion, and in malignancies, it can induce tumor seeding and secondaries. Most of the pathologies including tumors, related to blood vessels, and vascularity are well established. There are some conditions, wherein altered vascularity is one of the prime components along with other diagnostic components of an established disease. In such cases, these lesions are diagnosed with special names, with varying biological behavior and prognosis in comparison to that of established entity. However, there still are few similar conditions whose nature is uncertain due to the rarity of the lesion and the insufficient scientific evidence which eludes the diagnostician. Here is the report of two cases of ameloblastoma, an established entity, with significant vascularity whose nature is indeterminate.

Traumatic ulcerative granulomas are self-limiting ulcero-proliferative lesions emaluating malignancy clinically, thus causing anxiety for the patient. The etiopathogenesis of these lesions are unclear though trauma is ascertained to be a cause. Riga-Fede disease is considered a variant of the same, manifesting in infants. A clinically varying case series of TUGSE and RFD is reported, and the differential diagnosis discussed here.