Objectives: To assess the effect of exposure to flour dust on pulmonary function tests, prevalence of symptoms (respiratory, allergic/irritating) and parameters of allergic sensitization in terms of skin prick test, and bronchial hyper-responsiveness. Material and Methods: 43 bakers (with at least 2 years of occupational exposure) working at different bakeries in Ismailia city, Egypt; and 64 control subjects of comparable socio demographic characteristics were compared. All participants were subjected to an interview questionnaire, clinical chest examination, skin prick test, bronchial hyper-responsiveness test and measurements of pulmonary function parameters. Results: All respiratory and allergic symptoms were more prevalent among bakers compared to the control group, with the highest odds ratio for allergic symptoms (OR = 6.9; p < 0.0001) and dyspnea (OR = 6.3; p = 0.0004). Bakers had a higher percentage of SPT positive results with statistically significant difference between the two groups (p < 0.0001). Bakers had lower observed values compared to the control group with statistically significant difference for FVC, FEV 1 /FVC ratio, FEF 75% , and FEF 25-75% parameters. Conclusion: The present study suggested that occupational exposure to flour dust may affect respiratory irritation and sensitization, and reduce the pulmonary function tests such as FVC, FEV 1 , and FEV 1 /FVC ratio and FEF 25-75% .

Pulmonary function parameters of 21 cleaning/sanitary women workers who have never smoked, exposed to environmental tobacco smoke (ETS) at work were compared with 34 non-exposed women workers of comparable age and other work characteristics. The studied subjects were subjected to an interview questionnaire, pulmonary function measurements, bronchial responsiveness assessment and clinical chest examination. A higher prevalence of dyspnea was found (42.9%) among exposed compared to (14.7%) among the non-exposed workers (p=0.019), also wheezing (52.4% vs. 11.8%; p=0.001). Pulmonary measurements showed a lower FVC, FEV 1 /FVC and FEF 75 values among exposed compared to non-exposed (p<0.05), and a higher prevalence of borderline bronchial hyper-responsiveness (38.1% vs. 11.8%; p=0.021) in the exposed workers. This study provides evidence of adverse respiratory effects in sanitary/cleaning women workers associated with passive smoking in the workplace. The findings support a stricter implementation measures to protect respiratory health of all workers.

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