iabetes is a metabolic condition characterized by hyperglycemia and insufficient insulin production or activity. Since ancient times, the reishi mushroom (Ganoderma lucidum) has been utilized as a traditional herbal treatment. Aim of the study: investigate the effectiveness of Ganoderma lucidum extract (GLE) to ameliorate hyperglycemia and liver/kidney functions in streptozotocin-induced type 2 diabetic rats. Six groups of adult male Sprague-Dawley rats were formed at random. Group 1: Normal rats with a normal diet. Group 2: Diabetic rats by injection Streptozotocin (STZ) and fed without intervention as a model control group, Groups 3-6: GLE, diabetic rats with intervention groups receiving GLE at doses of 200, 400, 600, and 800 mg/kg BW via oral gavage for 28 days. After GLE intervention, blood samples were tested for changes in hyperglycemia, glycosylated hemoglobin, insulin, liver, and kidney functioning. Results: Within the first two weeks of GLE intervention, blood glucose levels were reduced, and insulin levels in diabetic rats in the GLE group were considerably higher at four weeks than in the positive control group. Furthermore, it was discovered that GLE intervention significantly improved the liver and kidney functioning of diabetic rats. Conclusion: This research suggests that GLE consumption may help reduce blood glucose levels by boosting insulin production. Meanwhile, GLE therapy was linked to a reduction in diabetes problems in type 2 diabetic rats by improving their liver and renal functioning.

The present study aims to determine the nutrients and nutraceuticals content and in vitro biological activities of reishi mushroom (Ganoderma lucidum) fruiting bodies. Data of the nutrients composition of Ganoderma lucidum powder indicated that crude fiber and carbohydrates were the most largest compounds (50.19 and 37.33%, respectively) followed by total protein (8.54 %), ash (2.03 %) and crude fat (1.91%.). Also, Ganoderma lucidum powder is rich in different estimated elements (K,

Nurses are qualified to provide effective nursing interventions in management of hypertensive patients and lower risk of cardiovascular disease; nurses-led interventions for hypertensive patients are measuring and monitoring blood pressure (BP); educate patients about importance of performing physical exercises, and select healthy diet as alkaline based diet. Eating more alkaline diet has many advantages as lowering blood pressure, lipid profile as cholesterol so improving cardiovascular health, moreover reducing body weight. The aim of the study: to examine the effect nurses-led interventions as intake alkaline-based diet on blood pressure, lipid profile and weight among patients with hypertension. Design: Quasi Experimental design. Setting: Medical outpatient clinic of Menoufia University Hospital, Egypt. Subject: Purposive samples of 100 hypertensive patients, they fulfill the inclusion criteria, 50 patients in each group (study and control). Tools: Three tools used to collect the current data; as follows: The tool (I): Interview questionnaire; Tool (II): Questionnaire for Alkaline -Based Diet. Tool (III): Physiological measurement. Results: the present results documented that; a highly significant difference was found between the two groups post intervention in relation to knowledge levels; blood pressure of the study group was lower than those of the control group after following the alkaline diet and water; also highly statistically significant differences were found between study and control groups at all measurements during post intervention in weight and all lipid profile variables except at the 3 rd measurement. Conclusion: consumption of alkaline diet and water had a good effect in reducing arterial blood pressure, body weight and blood lipids. Recommendation: replicate the study on large sample and establishing periodical alkaline diet programs with planned meals for hypertension, overweight and high blood lipids patients with continuous follow up.

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Background: Both iron deficiency anemia (IDA) and dyslipidemia are widely prevalent public health problems, especially in the Egyptian population. So, the purpose of this research was to study the correlation between dyslipidemia and IDA in Egyptian adults, Minoufiya Governorate population. Methods: In this comparative cross-sectional study, 110 adult with confirmed IDA and 110 healthy controls, in the age group 18-55 years were investigated for any possible changes in serum lipid profile i.e., triglycerides (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-c) and low density lipoprotein cholesterol (LDL-c) and very low density lipoprotein cholesterol (VLDL-c). Also, correlation between serum lipid profile and severity of anemia was also calculated. Results: The results are shown as mean± standard deviation. TG, TC, LDL-c and VLDL-c levels were found to be significantly (P <0.001) elevated in the IDA group (were 85.67±26.86, 123.79±30.54, 71.57±24.64 and 17.13±7.21 mg/dl) as compared to controls (107.89±22.40,158.45±26.34, 93.24±18.45 and 21.58±5.76 mg/dl). whereas level of HDL-c were found to be significantly (P <0.001) higher in patients (43.63±12.54 mg/dl) as compared to controls (35.09±13.05mg/dl). Correlation between lipid profile (TG, TC, and LDL) levels and severity of anemia (hemoglobin levels) showed positive and significant (P <0.01) values. Conclusion: These findings indicate that that the levels of serum lipid profile in Egyptian adults IDA were lower than the healthy control. However, to identify potential mechanisms of this relationship, further research are recommended to be carried out.