Background
Rheumatoid arthritis (RA) is a common disabling joint disease affecting both males and females. Sexual dysfunction (SD) is a common association with RA. The aim of this work was to study the prevalence and predictors of sexual dysfunction in male and female patients with rheumatoid arthritis.
Results
The mean age of female patients was 32.1 years and 39.7 years for males. The prevalence of sexual dysfunction was higher in RA female patients than controls, 62.1% versus 41.2% respectively (P ≤ 0.05). The prevalence of global sexual dysfunction was higher in RA male patients than controls, 63.8% versus 47.5% respectively (P ≤ 0.05). Predictors of sexual dysfunction in female RA patients were the number of children, BMI, disease duration, DAS score, HADs-D score, HAQ score, VAS score, joint deformity, and the number of drugs. Predictors of sexual dysfunction in male RA patients were age, disease duration, DAS score, HAQ score, VAS score, and the number of drugs.
Conclusion
SD is prevalent in RA patients. Disease activity, pain, depression, and disturbed quality of life affect nearly all domains of sexual functions in female and male patients.
Objective: The aim of this work was to evaluate Multidetector Computed Tomography (MDCT) findings
of hepatic manifestation in common malignant hematological disorders.
Materials and Methods: This retrospective study included 300 patients with different types of malignant
hematological disorders. They were 119 female and 181 male (mean age, 45.4 year; range, 5-70 years). The
most common hematological disorder was Non-Hodgkin lymphoma (NHL) detected in 192/300 (64%)
patients and then Hodgkin disease (HD) detected in 40/300 (13.3%) patients. All 300 patients had
ultrasonography. Clinical evaluation and laboratory assessment were done for all patients. Whole body and
triphasic abdominal CT scanning was performed on 64 MDCT systems.
Results: MDCT scanning revealed hepatic affection in 82/192 of NHL. All these 82 cases revealed
hepatomegaly and focal lesion detected in 36 cases. As regard Hodgkin disease (HD), hepatomegaly
detected in 22/40 cases and focal lesion detected in 8/40 cases. Hepatomegaly detected in 8/14 cases of
acute myeloid leukemia (AML) and focal lesion detected in 4/14 cases. In cases of chronic lymphocytic
leukemia (CLL), hepatomegaly detected in 6/22 cases with no detection of focal lesion.
Conclusion: Hepatic involvement is often observed in several malignant hematological disorders, resulting
in abnormalities in liver imaging studies. Malignant hematological disorders must be considered in
hepatomegaly and hepatic focal lesions either single or multiple. MDCT is the diagnostic modality of choice
for diagnosis and follow up of liver affection in different malignant hematological disorders.
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