Background Bipolar disorder, or manic-depressive illness, is a mental health condition characterized by mood shifts from severe depression to elevated mood or mania. Pregnant women with BD may experience manic or depressive episodes during gestation, delivery, or postpartum, so they are usually concerned about the effects of BD on their health and their fetal health. The aim of this systematic review is to determine the effects of BD on maternal health and fetal health, weight, and development. It also addresses how BD affects the probability of incidence of pregnancy and labor complications in women with bipolar compared to healthy controls. Methods Three electronic databases (Cochrane, PubMed, and ScienceOpen) were searched, and 1193 eligible studies were identified. After deduplication, screening, and manual search processes, we included only 7 studies. Descriptive analysis, meta-analysis, and calculation of the conditional probability of incidence for each pregnancy outcome were used to analyze the results. Results The findings of the included studies suggest that BD during pregnancy affects both fetal growth and maternal health by increasing the risk of giving birth to a neonate with some birth defects such as microcephaly, small for gestational age, and other congenital anomalies, in addition to causing some obstetric complications such as gestational hypertension, preterm labor, need for assisted delivery and others. Conclusion Bipolar disorder during pregnancy negatively affects mothers and their fetuses and increases the probability of incidence of obstetrics complications.

Background Menopause is the time that marks passing 12 months after last menstruation cycle in women between ages 40–50. Menopausal women have common symptoms such as: hot flashes, vaginal dryness, mood switching, depression and insomnia. The systematic review aims to determine the effects of different therapeutic and manual modalities on insomnia and depression in perimenopausal, menopausal, and post-menopausal women. Methodology After identifying our inclusion/exclusion criteria, adding our search term into 3 databases (PubMed, science open, and Cochrane), 3958 papers were identified. By using EndNote software, we excluded duplicates, unrelated, and non-full text papers. Thus, we included only 26 papers including 7 physiotherapy modalities: exercise, reflexology, footbath, walking, therapeutic and aromatherapy message, craniofacial message, and yoga. Results Most of the included modalities’ results showed a significant improvement in insomnia and depression symptoms in intervention group rather than control group. Conclusion Using non-pharmaceutical interventions such as physiotherapy have an overall positive impact on reducing insomnia and depression in menopause women.

Background Menopause is the time that marks passing 12 months after the last menstruation cycle in women between ages 40–50. Menopausal women often experience depression and insomnia that significantly impact their overall well-being and quality of life. This systematic review aims to determine the effects of different therapeutic physiotherapy modalities on insomnia and depression in perimenopausal, menopausal, and post-menopausal women. Methodology After identifying our inclusion/exclusion criteria, we conducted a database search in Ovid Embase, MIDRIS, PubMed, Cochrane, and ScienceOpen, where 4007 papers were identified. By using EndNote software, we excluded duplicates, unrelated, and non-full text papers. Adding more studies from manual search, we finally included 31 papers including 7 physiotherapy modalities: exercise, reflexology, footbath, walking, therapeutic and aromatherapy massage, craniofacial message, and yoga. Results Reflexology, yoga, walking and aromatherapy massage showed an overall significant impact on decreasing insomnia and depression in menopausal women. Most of exercise and stretching interventions also showed improvement in sleep quality but inconsistent findings regarding depression. However, insufficient evidence was found regarding the effect of craniofacial massage, footbath, and acupressure on improving sleep quality and depression in menopausal women. Conclusion Using non-pharmaceutical interventions such as therapeutic and manual physiotherapy have an overall positive impact on reducing insomnia and depression in menopausal women.

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