This study was conducted at the Dineye and Kassamma sites in the Zinder (Niger). Its objective is to determine the effect of the combination of FMNR and microdose fertilizers on millet productivity. The experimental device used is a Fisher block with ten (10) repetitions. The factor studied is soil fertilization with four (4) treatments (T): T1 consisting only of FMNR serving as a control; T2 which is a combination of FMNR and manure in microdose; T3 which is a combination of FMNR, manure and NPK in microdose and T4 which is a combination of FMNR and NPK in microdose. The growth parameters like height of the plant and the number of leaves were monitored per decade until maturity. At harvest, the yield components, namely: dry biomass, the weight of the ears and grains were evaluated. The results showed that height of the plants and the number of leaves were higher with T3. As for yields of stems, ears and grains, they were significantly higher in T3, followed by T4, T2 and T1 respectively. These results show that the combination of FMNR, organic manure and mineral manure in microdose made it possible to increase the yield of millet. This combination could therefore be popularized among agricultural producers in areas practicing FMNR to improve the productivity of their crops.