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Human herpes virus-6 (HHV-6) is a DNA virus with two known subtypes A and B. It is unique as its genome integrates into that of humans and is transmitted through the germ cells to the progeny, which is the major mode of vertical transmission (86%) compared to transplacental transmission (14%). 1 Chromosomally integrated HHV-6 (ciHHV-6) is diagnosed by the detection of HHV-6 DNA in hair follicles and/or nail clippings while it will be absent in transplacental infection. 2 We present a neonate who presented in shock after birth, was diagnosed with ciHHV-6Aassociated myocarditis and was successfully treated with artesunate, an antimalarial drug with antiviral properties.

We measured serum levels of 25-hydroxy vitamin D (25(OH) D) in 79 preterm neonates (?32 wk), and correlated it with serum ionized calcium (Ca++) levels at 48-72 h and serum phosphorus and alkaline phosphatase levels at 2-3 weeks of age. The mean (SD) 25 (OH)D level was 14.8 (7.0) ng/mL. 25(OH)D levels had a weak positive correlation with Ca++ (r=0.299) and phosphorus (r=0.186), and a negative correlation with alkaline phosphatase (r=-0.523).

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