Background Hair plays a significant role in shaping the appearance of an individual. Loss of hair can lead to serious effects on social esteem of an individual. The most common cause of hair loss is Androgenetic Alopecia (AGA).This hereditary disorder followed a specific pattern causing progressive thinning of hair in both Men and Women. Aims The aim of the current study is to compare and evaluate the efficacy of QR678 therapy versus PRP in the treatment of Male Androgenetic Alopecia. Since QR678 and QR678 Neo have been found to be formulations equivalent in efficacy, the results would be the same with either formulation. Methods A prospective, comparative, single‐blind study was carried out with 2 groups of 25 patients each. Intradermal injections of QR678 formulations and PRP were injected in group A and B respectively. Hair pull test, Video microscopic assessment, Global Photographic assessment was done and patient’s subjective assessment was done through questionnaire at the end of the study. Results were evaluated after 6 months and follow up was done till 1 year. Results 100% reduction in hair fall was noted at the end of 6 months in the QR678 group which was maintained for 1 year. Video microscopic evaluation showed that the hair density, terminal hair density, vellus hair density and shaft diameter were significantly better in QR678 group (P < .005) than the PRP group. Since QR678 and QR678 Neo formulatons are equivalent in efficacy, the results of tthis trial can be attributed to be the same, irrespective of the formulation used. Conclusion The bioengineered formulation of QR678 proved to be more beneficial for Male Androgenetic Alopecia (Male pattern hair loss) compared to PRP. A comparative study between QR678 and PRP with long term follow‐up will widen our spectra of knowledge.
Background: The changes in the mid face and lower face are among the most prominent features of the aging process. Intense focused ultrasound, known as the Ulthera System (Ulthera Inc., Mesa, AZ, USA), was designed to correct this process. It employs micro-focused ultrasound to cause discrete focal heating of the dermis and stimulates neocollagenesis and elastin remodeling. Methods: This study enrolled 50 adult patients of Indian ethnicity who opted for correction of mid face and lower face sagging by Ulthera. The subjects were treated using Ulthera 3.0 mm probes which targets deep dermis and 4.5 mm, which targets the superficial muscular aponeurotic system. All patients were evaluated for allergic reactions and side effects like scarring and nerve/muscle dysfunction. Investigators Global Aesthetic Improvement Scales Scores and Patients Global Aesthetic Improvement Scales Scores were used for analysis at 30 days, 60 days, 3 months, 6 months, and 1 year. Photographs were taken for detailed facial evaluation. Patients were asked to fill a self-assessment questionnaire. Results: At the end of 6 months, improvements in mid face and lower face were reported in 93% patients by blinded reviewers and 85% patients found the results to be satisfactory. The same results were maintained at the end of 1 year. Conclusion: Our study showed that substantial results can be achieved in overall aesthetic improvement of sagging of mid face and lower face with this modality using intense focused ultrasound which utilizes delivering of treatment at a single focal depth.
Background India is the country with the highest number of selfie‐related deaths. However, little is known whether this selfie craze contributes toward the behavioral changes and desire to undergo cosmetic procedures & surgery. Aim To analyse how taking, altering and posting selfies on social media, affects individuals’ self‐esteem, confidence, body image perception and mood in the Indian population. And to see whether the practice of taking selfies leads to the promotion of self‐image dysmorphia and an increased desire to undergo cosmetic surgical procedures. Methods A total of 300 participants from four Indian cities (75 each from Delhi, Hyderabad, Kolkata, and Mumbai) were included in the study. The study experimentally tested whether taking and posting selfie, with and without photograph retouching, elicits changes in mood, body image, and desire to undergo cosmetic surgery among young men and women. Results A significant increase in the level of social anxiety (P < .004), feeling of decrease in confidence (P < .002), feeling of decrease in physical attractiveness (P < .001) and the desire to undergo cosmetic surgery (P < .001) was noted in the experimental group. Also, all the findings were higher in women compared with men. Conclusion This first of its kind experimental study in the Indian population highlights the deleterious effects of uploading selfies on human mankind and well‐being. The prevalent obsessively looks‐oriented culture is engulfing our youth's innocence and warrants immediate attention. Few steps taken in the right direction and at the right time can save us from the disastrous effects of this selfie craze in future.
Purpose: To investigate visual performance during reading under different illumination sources.Methods: This experimental quantitative study included 40 (20 females and 20 males) emmetropic participants with no history of ocular pathology. The participants were randomly assigned to read a near visual task under four different illuminations (400-lux constant): compact fluorescent light (CFL), tungsten light (TUNG), fluorescent tube light (FLUO), and light emitting diode (LED). Subsequently, we evaluated the participants' experiences of eight symptoms of visual comfort. Results: The mean age of the participants was 19.86 ± 1.09 (range: 18-21) years. There was no statistically significant difference between the reading rates of males and females under the different illuminations (P = 0.99); however, the reading rate was fastest among males under CFL, and among females under FLUO. One way analysis of variance (ANOVA) revealed a strong significant difference (P = 0.001) between males and females (P = 0.002) regarding the visual performance and illuminations. Conclusion: This study demonstrates the influence of illumination on reading rate; there were no significant differences between males and females under different illuminations, however, males preferred CFL and females preferred FLUO for faster reading and visual comfort. Interestingly, neither preferred LED or TUNG. Although energy-efficient, visual performance under LED is poor; it is uncomfortable for prolonged reading and causes early symptoms of fatigue.
Background With the changing trends, more and more patients are opting for nonsurgical or minimally invasive options for reshaping the face. Noninvasive treatments such as incobotulinumtoxinA (Xeomin Cosmetic®; Merz Pharma Canada Ltd., Burlington, ON, Canada) are a preferred modality for reducing the volume of the muscle and therefore reducing the width of masseter. Aims To evaluate the efficacy of Xeomin treatment in long‐term management of bilateral masseter hypertrophy in Asian Indian patients. Patients/Methods A total of 30 patients were enrolled in the study and were injected with 30 U Xeomin on each side of face, at baseline. Fifteen patients received a second session of Xeomin injection at 12th week, and remaining 15 patients received an additional third session, at 12th and 24th weeks post the first injection, respectively. Follow‐up was done at 4th‐, 12th‐, 24th‐, and 36th‐week and at first‐ and second‐year follow‐ups. Results For the patients who received two injections, the maximum reduction of 26.85% was observed at 24th week, which was maintained as 20.04% reduction until second follow‐up year. The patients who received three injections exhibited very high reduction of 43.12% of masseter volume at 36th week, which was maintained at 38.72 % until the second follow‐up year. Three sessions of Xeomin injections were proved to be more effective in long‐term maintenance of reduced masseter volume than 2 sessions of injections. Conclusions Xeomin injections were found to be effective in long‐term management of bilateral masseter hypertrophy. This is the first of its kind paper, which evaluates the long‐term effects of Xeomin injections for the treatment of masseter hypertrophy.
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