The developments of monolithic materials rapidly in nowadays hold an impressively strong position in separation science as well as in other areas of chemistry. In this research are presented functionalization of PolyHIPE monolithic materials by tris(2-aminoethyl) amine. Monolithic polymer supports and scavengers were synthesized via nucleophilic displacement of chlorine in poly(4-vinyl benzyl chloride-co-divinylbenzene) as PolyHIPE materials. Porous copolymers of DVB/DVB were prepared by emulsion templating using high internal phase emulsions (HIPEs) as precursors for monoliths. The properties of the final products synthesized were functionalized with an amino group, at a different ratio of amine/chloromethyl groups, in different time refluxed were explored. PolyHIPE functionalized with tris(2-aminoethyl)amine to yield a product with high degrees of conversion. The extent of the functionalization reactions was investigated by a range of qualitative and quantitative techniques: FTIR, CHN analysis, potentiometric measurements, and (BET) measurements have been performed.

4‐Benzothiazolylamino‐6‐methyl‐2H[1]‐pyran‐2‐one 6a , 4‐(4‐Methylbenzothiazolylamino)‐6‐methyl‐2H[1]‐pyran‐2‐one 6b , 4‐(5,6‐dimethylbenzothiazolylamino)‐6‐methyl‐2H[1]‐pyran‐2‐one 6c and substituted 4‐(Benzothiazolylamino)‐6‐methyl‐3‐nitro‐2H[1]‐pyran‐2‐ones 6(d, e) are synthesized by condensation of 4‐Chlor‐6 methylpyran‐2‐ones (2, 4) and corresponding benzithiazolylamines 5(a‐e) under reflux reaction conditions. The antibacterial activity of products 4(a‐d) against Staphylococcus aureus, Clebsiella and Escherichia coli were investigated. Compounds 6(a‐e) showed light bactericide activity against Staphylococcus aureus, Escherichia coli and Clebsiella. Compounds 6e and 6c were more active against Staphylococcus aureus. Compounds 6d and 6b exhibited the strongest activity against Clebsiella, whereas 6e was more active against Escherichia coli. In general there was a driect positive correlation between increasing concentration of the compound and anitbacterial activity.