Functional colloidal nanoparticles capable of converting between various energy types are finding an increasing number of applications. One of the relevant examples concerns light-to-heat-converting colloidal nanoparticles that may be useful for localized photothermal therapy of cancers. Unfortunately, quantitative comparison and ranking of nanoheaters are not straightforward as materials of different compositions and structures have different photophysical and chemical properties and may interact differently with the biological environment. In terms of photophysical properties, the most relevant information to rank these nanoheaters is the light-to-heat conversion efficiency, which, along with information on the absorption capacity of the material, can be used to directly compare materials. In this work, we evaluate the light-to-heat conversion properties of 17 different nanoheaters belonging to different groups (plasmonic, semiconductor, lanthanide-doped nanocrystals, carbon nanocrystals, and metal oxides). We conclude that the light-to-heat conversion efficiency alone is not meaningful enough as many materials have similar conversion efficienciesin the range of 80–99%while they significantly differ in their extinction coefficient. We therefore constructed their qualitative ranking based on the external conversion efficiency, which takes into account the conventionally defined light-to-heat conversion efficiency and its absorption capacity. This ranking demonstrated the differences between the samples more meaningfully. Among the studied systems, the top-ranking materials were black porous silicon and CuS nanocrystals. These results allow us to select the most favorable materials for photo-based theranostics and set a new standard in the characterization of nanoheaters.

The spectroscopic properties of different infrared-emitting neodymium-doped nanoparticles (LaF 3 :Nd 3þ , SrF 2 :Nd 3þ , NaGdF 4 : Nd 3þ , NaYF 4 : Nd 3þ , KYF 4 : Nd 3þ , GdVO 4 : Nd 3þ , and Nd:YAG) have been systematically analyzed. A comparison of the spectral shapes of both emission and absorption spectra is presented, from which the relevant role played by the host matrix is evidenced. The lack of a "universal" optimum system for infrared bioimaging is discussed, as the specific bioimaging application and the experimental setup for infrared imaging determine the neodymiumdoped nanoparticle to be preferentially used in each case. V C 2015 AIP Publishing LLC.

Lanthanide doped, up-converting nanoparticles have found considerable interest as luminescent probes in the field of bio-detection. Although the nanoparticles (NPs) have already been successfully applied for fluorescent bio-imaging and bio-assays, the efficiency of the up-conversion process seems to be the bottle-neck in rigorous applications. In this work, we have shown enhancement of the up-conversion in colloidal α-NaYF₄:Yb(3+), Tb(3+) doped nanocrystals owing to passivation of their surface. We have studied quantitatively the influence of the shell type (NaYF₄ and CaF₂), its thickness, as well as the shell deposition method (i.e. single thick shell vs. multi-layer shell) on the luminescent properties of the nanoparticles. The results showed that up to 40-fold up-conversion intensity enhancement may be obtained for the core-shell nanoparticles in comparison with the bare core nanoparticles, irrespective of the shell type and deposition method. Moreover, the suitability of the NaYF₄:Yb(3+), Tb(3+) core-shell NPs for multi-color emission and spectral multiplexing has been presented.