No abstract

Tetrazole derivatives R 0310 Efficient Synthesis of Olmesartan Medoxomil, an Antihypertensive Drug. -The tailored process allows the synthesis of the title angiotensin receptor antagonist on a large scale with 50% overall yield and with excellent control of the impurity profile in all steps. -(BABU, K. S.; REDDY, M. S.; TAGORE, A. R.; REDDY, G. S.; SEBASTIAN, S.; VARMA, M. S.; VENKATESWARLU, G.; BHATTACHARYA, A.; REDDY, P. P.; ANAND*, R. V.; Synth. Commun. 39 (2009) 2, 291-298; Cent. Excellence, Dr. Reddy's Lab., Hyderabad 500 072, India; Eng.) -K. Woydowski