The extraction of Flavonoids from dried ginger ( Zingiber officinale Ros.) roots in addition of non-flavonoids parts (oils and defatted) were studied against H 2 O 2 induced oxidative stress in the serum of male rats for 15 day.Fifty male rats with age of 3-4 months and weight of 225-300 g were divided into 5 groups : group (1): control group received drinking tab water and ideal diet, group (2): received 0.5% H 2 O 2 in drinking tab water , group (3): received 0.5% H 2 O 2 and oral dose of 15 mg/ kg of BW. flavonoids once daily, group (4): received 0.5% H 2 O 2 and oral dose of 30 mg/ kg BW flavonoids once daily. Group (5): received 0.5% H 2 O 2 and the experimental diet ( 50 g non-flavonoids part / kg diet).H 2 O 2 treated group showed elevation in serum cholesterol, malondialdehyde (MDA), peroxynitrite radical levels and reduction in glutathione (GSH), vit C, albumin, calcium, and phosphorus levels compared with the control group (p≤ 0.05). Treatment with ginger extracts counteracted the oxidative stress induced by H 2 O 2 by reducing the levels of cholesterol, MDA and peroxynitrite and enhancing the levels of GSH, vit C, albumin and calcium compared with the H 2 O 2 treated group (p≤ 0.05). Treatment with non flavonoids part, by means of experimental diet, showed decreasing in the MDA, peroxynitrite, phosphate levels and increasing in vit C level compared with the H 2 O 2 treated group (p≤ 0.05). The results of the present study provided the protective effects of the ginger extract by increasing antioxidant defense and suppression free radicals production in the serum.

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Vegetable oils are considered to be active in modulation of the blood lipid profile and profilacting from cardiovascular diseases, oils extracted from plants (sunflower seeds) may also contains some polar substances which can interferes with their action, if these oils are exposed to some washing processes with worm water, these substances will be removed. A thirty adult albino male rats were divided into five groups and exposed to a hyperlipidemic and hypercholesterolemic diet (animal fats 16% of total calories) and H 2 O 2 (0.5%) in the water for a 30 days for induction of hypercholesterolemia in addition to 15 days in which. sunflower oil are administered orally as a crude and washed oils at a doses of 300 and 600 mg/ kg body weight. There was no significant effect of the washing process on the nutritional status but there were a decrease in total cholesterol TC (50 %), phospholipids PL (42%), low density lipoproteins LDL-c (74%) and elevation in high density lipoproteins HDL-c (70%) resulted from the treatment with washed oil (600 mg/ kg body weight) in addition to decrease in liver malondialdehyde (MDA) content. In conclusion, the washing process of sunflower oil will improve it's hypocholesterolemic and antioxidant effects.

is highly toxic herbicide with no specific antidote. this study was conducted to evaluate the therapeutic potency of dexamethasone (Dx) on the kidney function tests in experimental paraquat intoxication in male rats. Three groups of rats were subjected to this trial, control, PQ group (50 mg/ kg orally) and PQ with Dx (50 mg/ kg orally, 4 mg/ kg ip. respectively) throughout 15 days. Results revealed that treatment with PQ caused an elevation in kidney function indices as well as sodium ion and decrease in each of potassium, calcium ions and inorganic phosphate compared to control whereas treatment with Dx decreased (p 0.05) the concentration of both creatinine and inorganic phosphate and elevated the concentrations of blood urea nitrogen and calcium in comparison with values of PQ-treated rats, Dx did not affect the concentrations of uric acid, sodium and potassium. In conclusion, the treatment of PQ-induced toxicity with Dx in rats has limited value in correction of most kidney function tests.