Three new sativene sesquiterpenoids, bipolenins A-C (1-3), together with two known analogs (4 and 5), were obtained from cultures of endophytic fungus Bipolaris eleusines. The structures of new compounds were elucidated on the basis of extensive spectroscopic analyses. Compound 2 showed weak inhibitory activities against lung cancer A-549 and breast cancer MCF-7 with IC50 values of 33.2 and 19.1 μmol, respectively.

Two sativene sesquiterpenoid-xanthone adducts from potato endophytic fungus Bipolaris eleusines

Two new seco-sativene sesquiterpenoids, bipolenins D (1) and E (2), a new seco-longifolene sesquiterpenoid, bipolenin F (3), together with three known analogues (4–6), were obtained from cultures of endophytic fungus Bipolaris eleusines. Their structures were established by MS and NMR data. Compounds 1–6 showed no activity to five human cancer cell lines.Electronic supplementary materialThe online version of this article (doi:10.1007/s13659-016-0116-4) contains supplementary material, which is available to authorized users.

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