Background: Coronary Artery Disease (CAD) is one of the major causes of mortality in most countries. Electrocardiography (ECG) and myocardial perfusion imaging (MPI) are non-invasive disgnostic tests for CAD. Finding a relationship between abnormal findings in the baseline ECG and MPI findings can be helpful in better diagnosis of CAD. Materials and Methods: The present study examined ECG of patients who underwent MPI and categorized them into three groups: normal ECG, abnormal ST-T change, and abnormal Q or fragmented QRS. The quantitative and semi-quantitative parameters as well as visual interpretation of MPI were compared among the three groups. Results: Finally, 230 patients entered the study, including 92 patients (40.0%) with normal ECG, 86 patients (37.4%) with ST-T changes and 52 patients (22.6%) with fQRS-Q complex abnormality. In total, 77 patients (33.5%) had positive MPI scan. There were significant differences between the normal and ST-T subgroups with Q-fQRS group for all quantitative and semi-quantitative variables, however, normal and ST-T groups were significantly different only in terms of SSS, SDS and TPDs. Frequency of abnormal MPI was significantly higher in Q-fQRS group. Conclusion: The results of this study showed that myocardial ischemia is more frequent in patients with baseline ST-T ECG changes. In addition, Q-fQRS abnormality is associated with higher rates of both myocardial scar and ischemia in MPI.

Lung cancer incidence is increased among the younger population, and various factors are being responsible for that [1,2]. Accompaniment of myasthenia gravis with solid tumors like lung cancer is reported [3,4]. A 28 year old housewife with persistent cough and exertional shortness of breath diagnosed with squamous cell carcinoma, she also has a history of seropositive myasthenia gravis, diagnosed 12 years ago, with right sided petosis, hoarseness and dysphagia. It seems that a history of thymoma increases the chance of extra thymic malignancies [3][4][5]. Occurrence of cancer in these patients might be synchronous or a few years before or after the onset of MG. Long-term exposure to corticosteroids and the 12-year history of MG are seemingly the leading causes of cancer development in this young female.