This study explores and examines the effects of the curriculum and content of entrepreneurship as well as perceived university support on the entrepreneurial drive of students who are majoring in business administration. The research was conducted with a sample of 156 senior students at the most popular universities in the business fields in Hanoi, the capital city of Vietnam. Based on a quantitative methodology using PLS-SEM, the study has revealed that the curriculum and content of entrepreneurship significantly affected the students’ entrepreneurial drive. However, this study has not found a relationship between perceived university support and entrepreneurial drive. Based on the discussion of the findings, the study has generated novel suggestions for universities and business faculties with similar characteristics in completion of their curriculum and content of entrepreneurship. Furthermore, this study also suggested further research directions to develop the appropriate approaches to university support.   Received: 21 June 2022 / Accepted: 25 August 2022 / Published: 2 September 2022