Background: Catheter-associated urinary tract infections (CAUTIs) are an expensive and harmful reality for patients in rehabilitation hospitals. Reduction in incidence of CAUTIs depends on duration of catheterization, appropriate catheter care and hand hygiene policy compliance. The effectiveness of HealthSouth indwelling catheter-related infection control policies were assessed through a case-series study.Methods: HealthSouth catheter utilization rates and CAUTI incidence rates for 2014 were collected using Electronic Medical Services (EMS). These rates were compared to the National Healthcare Safety Network (NHSN) averages for similar type of facilities across the nation. Binomial confidence intervals were calculated and rates were compared using the Z-test. Hand hygiene compliance rates for HealthSouth were collected for the 1 st quarter of 2015 and compared to the national average. Results:During the 1 st quarter of 2015, E. coli (27.7%), E. faecalis (16.9%), and K. pneumonia (12.3%) were the most common identified organisms growing at a minimal concentration of 100,000 CFU per milliliter. HealthSouth 12-month catheter utilization rate was 0.05 per patient day for 2014. A significant difference was found between this HealthSouth rate and the 2013 NHSN national catheter utilization rate of 0.08 per patient day (p < 0.001). HealthSouth 12-month CAUTI rate was 0.90 per 1,000 urinary catheter days for 2014. HealthSouth CAUTI rate was not statistically different from the 2013 NHSN national CAUTI rate of 2.1 per 1,000 urinary catheter days (p = 0.390). The hand-hygiene compliance rate (78%) for HealthSouth for the 1st quarter of 2015 was lower than the national average compliance rate (45%).