PurposeCompare wide-field Optomap imaging and optical coherence tomography (OCT) with clinical examination in diabetic retinopathy (DR).MethodsPatients referred from Diabetic Eye Screening Programmes to three centres underwent dilated ophthalmoscopy and were assigned a DR grade. Wide-field colour imaging and OCT were then examined by the same clinician at that visit and a combined grade was assigned. Independent graders later reviewed the images and assigned an imaging-only grade. These three grades (clinical, combined, and imaging) were compared. The method that detected the highest grade of retinopathy, including neovascularisation, was determined.ResultsTwo thousand and forty eyes of 1023 patients were assessed. Wide-field imaging compared with clinical examination had a sensitivity and specificity of 73% and 96%, respectively, for detecting proliferative DR, 84% and 69% for sight-threatening DR, and 64% and 90% for diabetic macular oedema. Imaging alone found 35 more eyes with new vessels (19% of eyes with new vessels) and the combined grade found 14 more eyes than clinical examination alone.ConclusionsAssessment of wide-field images and OCT alone detected more eyes with higher grades of DR compared with clinical examination alone or when combined with imaging in a clinical setting. The sensitivity was not higher as the techniques were not the same, with imaging alone being more sensitive. Wide-field imaging with OCT could be used to assess referrals from DR screening to determine management, to enhance the quality of assessment in clinics, and to follow-up patients whose DR is above the screening referral threshold but does not actually require treatment.
In the present research work, 300 meat samples (50 beef, 50 carabeef, 50 chevon, 50 mutton, 50 pork and 50 chicken) collected from the municipal slaughter houses and the retail meat shops from Hyderabad Karnataka region of Karnataka state, India, were analyzed for the microbiological quality; standard plate count and isolation and confirmation of Staphylococcus, Salmonella, E. Coli, Listeria and Clostridium by selective plating, microscopic examination and biochemical characterization. As per Food Safety and Standards (FSS) regulations 2011, of the samples analyzed, 89 (29.66%) (21 beef, 26 carabeef, 9 chevon, 7 mutton, 14 pork and 7 chicken) samples exceeded the limit of 10,000 CFU/gram of total viable count. Twenty (6.66%) samples (8 beef, 9 carabeef and 3 pork) exceeded the limit for Staphylococcus (100/gram maximum), 15 (5%) samples (9 pork, 4 chicken and 2 mutton) exceeded the limit for Salmonella (absent in 25 gram) and 22 (7.33%) samples (11 pork, 4 chicken, 4 beef and 3 carabeef) exceeded the limit for E. Coli (100/gram maximum). None of the samples were positive for Listeria and Clostridium spp. The finding in this study specifies the probable contamination during farming and on-floor slaughtering and accentuates the requirement of the upgrading the municipal slaughter houses and training of retail outlet sellers.
Connective tissue tumors of pancreas are uncommon, among them pancreatic schwannoma is very rare tumor, very few cases were reported in literature. Aggressive resections like whipple's procedure, or distal pancreatectomy are not necessary for pancreatic schwannoma as it rarely goes to malignant change and simple enuclation is sufficient.In our patient pancreatic schwannoma is associated with simple cyst in liver and absence of one kidney. Here, we are presenting a case of pancreatic schwannoma treated by simple enucleation.
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