Background
Approximately 50% of patients with colorectal cancer (CRC) develop metastases most commonly in the liver. Liver transplantation (LT) can be used in certain cases of primary liver malignancy or in metastatic diseases, such as Neuroendocrine tumors. However, there are controversies regarding LT as a treatment option for liver metastasis from CRC due to poor outcomes in previously reported cases.
Case presentation
We report a 37-year-old male who underwent resection of the left-sided colon due to cancer and was found to have synchronous liver metastasis for which he received chemotherapy. Later, he underwent a right hepatectomy, which was complicated by insufficient liver remnant function despite the preserved liver perfusion. Therefore, salvage liver transplantation was performed successfully with a good long-term outcome.
Conclusions
Many studies examined the survival and quality of life in patients undergoing liver transplantation for unresectable colorectal liver metastasis; these studies include the SECA Study (secondary cancer) and others with favorable outcomes. We reviewed the literature and compared the outcomes of some of these studies in this article. Our case emphasizes that liver transplantation could be an option for some colon cancer liver metastasis (CLM) patients, specifically, as a salvage procedure. Thus, more research is needed to develop selection criteria for patients who may benefit from liver transplantation.
Transplanting horseshoe kidneys is challenging and has higher complication rates due to the unusual anatomy of the vascular and urinary collecting systems. Most centers avoid using these kidneys for transplantation. However, if chosen carefully, these organs can be used successfully to reduce organ shortage. In this paper, we will describe the technique of procurement of horseshoe kidneys from cadaveric donors, back table preparation, and its successful implantation in a recipient. With good planning and skillful surgical techniques, horseshoe kidneys can be successfully transplanted in suitable recipients. If properly selected, these kidneys can be used to reduce the organ scarcity and diminish waitlist morbidity and mortality.
Introducere: Rinichii cu artere multiple reprezintã o provocare deosebitã pentru chirurg, atât în timpul nefrectomiei la donator cât şi al transplantului renal. Scopuri: Scopurile acestui studiu sunt evaluarea rezultatelor atât a donatorilor cât şi a recipienţilor rinichilor cu artere multiple procuraţi pe cale laparoscopicã. Pacienţi şi Metodã: Am analizat retrospectiv datele medicale a tuturor recipienţilor şi a donatorilor vii care au donat rinichi pe cale laparoscopicã între aprilie 2009 şi decembrie 2014. Detaliile intraoperatorii şi evoluţia imediatã au fost comparate între donatorii şi recipienţii de rinichi cu artere multiple şi donatorii şi recipienţii de rinichi cu arterã renalã unicã. Rezultate: Dintr-un total de 250 donatori la care s-a practicat nefrectomia laparoscopicã 43 (17,2%) au avut artere renale multiple. Timpul operator mediu a fost semnificativ statistic mai lung în grupul cu artere multiple (168,1 min vs 135,3 min; p=0,001), cu toate acestea durata ischemiei calde, respectiv rece, au fost similare în cele douã grupuri. Nu au fost consemnate complicaţii la donatorii din ambele grupuri, nici conversii la nefrectomia pe cale deschisã. Durata spitalizãrii postoperatorii a fost similarã pentru cele douã grupuri. Deasemenea nu a existat nici o diferenţã semnificativã statistic între rata funcţionãrii imediate a grefelor renale din ambele grupuri. Concluzii: Nefrectomia laparoscopicã la donatorii cu artere multiple este o procedurã sigurã şi nu are un impact semnificativ asupra evoluţiei ulterioare a donatorului sau a funcţionãrii grefei renale.
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