The synthesis of di(1H-tetrazol-5-yl)methane (1, 5-DTM), starting from commercially available sodium azide and malononitrile, is described. This tetrazole was characterized and investigated for use as a neutral nitrogen-rich ligand in various energetic transition metal complexes: ([CuCl(5-DTM)]·2HO (2), [Co(HO)(5-DTM)]Cl (3), [Ni(HO)(5-DTM)]Cl (4), [Co(HO)(5-DTM)](NO) (6), [Ni(HO)(5-DTM)](NO) (7), [Zn(HO)(5-DTM)](NO) (8), {[Cu(SO)(5-DTM)(HO)(5-DTM)]·2HO} (9), [Cu(HO)(5-DTM)](NO) (11), [Cu(NO)(5-DTM)]·2HO (12), [Cu(NO)(5-DTM)] (13), [Cu(HO)(5-DTM)](ClO) (14), and [Cu(ClO)(5-DTM)] (15). Obtained coordination compounds were characterized using single crystal X-ray diffraction (except for 7 and 13), IR spectroscopy, elemental analysis, and differential thermal analysis. The sensitivities to external stimuli (impact, friction, electrostatic discharge) were determined. Complexes 12 and 13 were tested for their ignitability by laser irradiation.
The first asymmetric total synthesis of the meroterpenoid (À)-merochlorin Ai sd escribed. The route features enantiospecific gold-catalyzed tandem 1,3-acyloxy migration/ Nazarov/aldol reaction sequence to furnish the bicyclo-[3.3.0]octane core in as ingle step from al inear propargylic 1,3-enyne aldehyde.After completion of the central skeleton by reductive enol lactone rearrangement, late stage Diels-Alder cycloaddition/aromatization sequence installed the resorcinol. An additional salient feature of the synthesis is the assignment of the absolute configuration, whichh ad not been determined previously.
The first asymmetric total synthesis of the meroterpenoid (−)‐merochlorin A is described. The route features enantiospecific gold‐catalyzed tandem 1,3‐acyloxy migration/Nazarov/aldol reaction sequence to furnish the bicyclo[3.3.0]octane core in a single step from a linear propargylic 1,3‐enyne aldehyde. After completion of the central skeleton by reductive enol lactone rearrangement, late stage Diels–Alder cycloaddition/aromatization sequence installed the resorcinol. An additional salient feature of the synthesis is the assignment of the absolute configuration, which had not been determined previously.
The difunctionalization of unactivated, terminal olefins through intermolecular addition of α-bromoketones, -esters, and -nitriles followed by formation of 4- to 6-membered heterocycles with pendant nucleophiles is reported.
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