Eosinophilic gastroenteritis is considered an uncommon disease with a low incidence rate that remains as a diagnostic challenge for the clinician, in spite of the fact that seventy years have passed since its original description. Hereby we present the case of a 29-year-old male without history of allergies who was evaluated for unspecific gastrointestinal symptoms, without relevant findings on physical examination and presenting an initial complete blood count (CBC) with severe eosinophilia. The patient was evaluated and the diagnosis of eosinophilic gastroenteritis was confirmed by histopathological findings. The relevance of the case resides in highlighting the lack of guidelines or consensus for histological diagnosis being virtually the only one available. To a similar extent, treatment evidence is based on case series with a reasonable number of patients and case reports.

Iodine deficiency is an important clinical and public health problem. Its prevention begins with an adequate intake of iodine during pregnancy. International agencies recommend at least 200 mg iodine per d for pregnant women. We assessed whether iodine concentrations in the amniotic fluid of healthy pregnant women are independent of iodine intake. This cross-sectional, non-interventional study included 365 consecutive women who underwent amniocentesis to determine the fetal karyotype. The amniocentesis was performed with abdominal antisepsis using chlorhexidine. The iodine concentration was measured in urine and amniotic fluid. The study variables were the intake of iodized salt and multivitamin supplements or the prescription of a KI supplement. The mean level of urinary iodine was 139·0 (SD 94·5) mg/l and of amniotic fluid 15·81 (SD 7·09) mg/l. The women who consumed iodized salt and those who took a KI supplement had significantly higher levels of urinary iodine than those who did not (P¼ 0·01 and P¼0·004, respectively). The urinary iodine levels were not significantly different in the women who took a multivitamin supplement compared with those who did not take this supplement, independently of iodine concentration or multivitamin supplement. The concentrations of iodine in the amniotic fluid were similar, independent of the dietary iodine intake. Urine and amniotic fluid iodine concentrations were weakly correlated, although the amniotic fluid values were no higher in those women taking a KI supplement. KI prescription at recommended doses increases the iodine levels in the mother without influencing the iodine levels in the amniotic fluid. Iodine: Amniotic fluid: PregnancyAlthough marked physiological differences exist between the maternal and fetal thyroids, both systems interact through the placenta and the amniotic fluid, modulating the transfer of iodine and small but biologically important amounts of thyroid hormones from the mother to the fetus (1) . Prior to the end of the first trimester, when the fetal thyroid gland and the pituitary-thyroid axis become functional, the thyroid hormones required by the fetus are all obtained from the maternal circulation (2) .The volume and content of amniotic fluid is the result of a balance between the urine and the fetal pulmonary fluids, the amount of fluid that is reabsorbed or swallowed by the fetus (3) and transfer of water and solutes across the fetal membranes.Animal studies have demonstrated a rapid exchange between the mother and fetus and between the fetus and the amniotic fluid, suggesting that the amniotic fluid could act as an iodine reservoir for the fetus (4) . Etling et al. (5) found high levels of iodine in the amniotic fluid of women who had undergone urographic examinations with iodized contrast materials or who had been exposed to iodized agents vaginally. However, few studies have investigated the iodine concentration in the amniotic fluid of human subjects and these only examined the influence of the overload of high iodine concentrations. ...

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A substantive amendment to this systematic review was last made on 28 August 2002. Cochrane reviews are regularly checked and updated if necessary. ABSTRACTBackground: The cervical cap and the diaphragm are vaginal barrier contraceptive methods that prevent pregnancy by covering the cervix. The two devices also act as a reservoir for spermicide. The cervical cap is smaller and can remain in place longer than the diaphragm. Two types of cervical caps, the Prentif cap and the FemCap, have been compared to the diaphragm in randomized controlled trials.

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