Necrobiotic xanthogranuloma may clinically mimic commoner tumours such as Warthin's tumour. Once diagnosed, the clinician should be wary of extracutaneous manifestations and paraproteinaemias. Because of the variability of presentation, there is no consensus on the best treatment for necrobiotic xanthogranuloma, which may include surgery, chemotherapy, interferon, plasmapheresis and radiation therapy.
Merkel cell carcinoma (MCC) is an uncommon highly aggressive skin malignancy with an increased tendency to recur locally, invade regional lymph nodes, and metastasize distally to lung, liver, brain, bone, and skin. The sun-exposed skin of head and neck is the most frequent site of involvement (55%). We report the case of a 63-year-old Caucasian male patient who presented with a recurrent left inguinal mass for the third time after surgical resection with safe margins and no postoperative radio- or chemotherapy. The presented mass was excised, and pathological diagnosis revealed recurrent MCC. The patient underwent postoperative radiation therapy, and 6 months later, he developed a right groin mass which was resected and pathological diagnosis confirmed metastatic MCC. Six months later, patient developed an oropharyngeal mass which was unresectable, and pathological biopsy confirmed metastatic MCC. Patient was offered palliative radio- and chemotherapy. In this paper, we also present a brief literature review on MCC.
Myxoinflammatory fibroblastic sarcoma (MIFS) was first described in 1998 as an inflammatory myxohyaline tumor of distal extremities. 1 It is a low-grade subcutaneous soft tissue sarcoma occurring mostly in the distal limbs 2 and less frequently in nonacral sites like the torso, neck, and head. 3 According to the American Cancer Society, more than 13,000 new cases of soft tissue tumors occurred in the United States in 2022, accounting for 0.7% of all cancer cases. [4][5][6] MIFS tends to occur in young to middle-aged people; mean patient age is 40 years, and the sex ratio is 1:1. 7 A review of 21 articles concluded that there is no predilection for a specific age group or sex. 8 MIFS is locally aggressive and poses a high risk for local recurrence and a low risk for metastasis. 9 The radiological and histopathological features of MIFS are still not well defined. Herein, we report the radiological and histopathological features and management of MIFS in a 33-year-old woman with MIFS in the hand, which may provide better understanding of the disease.
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