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Degenerated red blood cells (ghost cells) cause secondary open-angle glaucoma by blocking the outflow through the trabecular meshwork (Campbell et al. 1976). After a vitreous hemorrhage, red blood cells degenerate (Campbell et al. 1976). They lose their intracellular hemoglobin and appear as small and tan-colored intraocular bodies with some denatured clumped hemoglobin called Heinz bodies (Campbell et al. 1976). The ghost cells migrate into the anterior chamber through a disrupted anterior hyaloid face. Ghost cells are more rigid compared to normal red blood cells, which is a major reason for obstruction of the trabecular meshwork (Campbell et al. 1976; Quigley and Addicks 1980).

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