Background and Aims. Caffeine mouth rinsing has emerged as an alternative to oral caffeine consumption for improving performance without provoking lower gastrointestinal distress. However, it remains unclear if hydration status and sweat rate are negatively affected by caffeine mouth rinsing. This study is aimed at evaluating the effects of 10 seconds of caffeine mouth rinsing (1.2% anhydrous caffeine solution) on hydration status and sweat rate following a 10 km run trial. Methods. Ten recreationally trained runners (30.1±6.4 y) volunteered to participate in this double-blind, placebo-controlled, and crossover research study. Participants completed two 10 km run trials separated by approximately one week. Immediately prior to running, participants completed a 10-second mouth rinse protocol with either 300 mg of caffeine or microcrystalline cellulose (placebo) diluted in 25 mL of water. The effects of caffeine mouth rinsing on hydration status and sweat rate were assessed following a 10 km run trial. Results. Sweat rate (placebo: 15.34±9.71 vs. caffeine: 11.91±6.98 mL·min−1; p=0.39), dehydration (placebo: 1.20±0.57 vs. caffeine: 1.49±0.29%; p=0.15), and hydration (placebo: 15.32±9.71 vs. caffeine: 11.89±6.99 mL·min−1; p=0.37) measures were not significantly different between trials. Conclusion. Caffeine mouth rinse does not appear to alter the hydration status or sweat rate following a 10 km run.
The triglyceride-to-high-density lipoprotein-cholesterol (TG/HDL-c) ratio is a simple but effective indicator of metabolic imbalance that characterizes metabolic syndrome (MetS) and can consequently indicate a higher cardiovascular risk. It may, therefore, be useful in identifying a high risk for cardiometabolic diseases according to the onset of obesity. The aim of this study was to evaluate the association between MetS and the stage of life at obesity onset and to establish the cutoff point for the TG/HDL-c ratio as a marker of MetS in women with severe obesity. Forty-seven women who were to undergo bariatric surgery were evaluated. Anthropometric and metabolic parameters were measured, and the TG/HDL-c ratio was calculated. The volunteers were grouped according to their stage of life at obesity onset. A receiver operating characteristic (ROC) curve was constructed to define cutoff points for the TG/HDL-c ratio as predictors of MetS. Women who developed obesity early (during infancy/adolescence) had higher weight (p = 0.008), body mass index (p = 0.031), and hip circumference (p = 0.036) than those who developed obesity later (in adulthood); however, no association was found between obesity onset and MetS. The cutoff points for the TG/HDL-c ratio that were established for those who developed early or late obesity were 2.30 and 2.19, respectively. Although the stage of life at the onset of obesity was not related to MetS, different cutoff points for the TG/HDL-c ratio were observed.
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