No abstract

Peripheral nerve injuries impair the patient’s functional capacity, including those occurring in the facial nerve, which require effective medical treatment. Thus, we investigated the use of heterologous fibrin biopolymer (HFB) in the repair of the buccal branch of the facial nerve (BBFN) associated with photobiomodulation (PBM), using a low-level laser (LLLT), analyzing the effects on axons, muscles facials, and functional recovery. This experimental study used twenty-one rats randomly divided into three groups of seven animals, using the BBFN bilaterally (the left nerve was used for LLLT): Control group—normal and laser (CGn and CGl); Denervated group—normal and laser (DGn and DGl); Experimental Repair Group—normal and laser (ERGn and ERGl). The photobiomodulation protocol began in the immediate postoperative period and continued for 5 weeks with a weekly application. After 6 weeks of the experiment, the BBFN and the perioral muscles were collected. A significant difference (p < 0.05) was observed in nerve fiber diameter (7.10 ± 0.25 µm and 8.00 ± 0.36 µm, respectively) and axon diameter (3.31 ± 0.19 µm and 4.07 ± 0.27 µm, respectively) between ERGn and ERGl. In the area of muscle fibers, ERGl was similar to GC. In the functional analysis, the ERGn and the ERGI (4.38 ± 0.10) and the ERGI (4.56 ± 0.11) showed parameters of normality. We show that HFB and PBM had positive effects on the morphological and functional stimulation of the buccal branch of the facial nerve, being an alternative and favorable for the regeneration of severe injuries.

To evaluate the influence of bioactive glass and photobiomodulation therapy (PBMT) in calvarial bone repair process in rats submitted to zoledronic acid therapy. Methods: Twenty-four rats were selected and treated with the dose of 0.035 mg/kg of zoledronic acid every two weeks, totalizing eight weeks, to induce osteonecrosis. After the drug therapy, surgical procedure was performed to create 5-mm diameter parietal bone defects in the calvarial region. The rats were then randomly assigned to groups according to the following treatments: AZC: control group, treated with blood clot;

Objetivo: Relatar o caso de extensa perda tecidual traumática do lábio por auto mordida após bloqueio do nervo alveolar inferior para exodontia de terceiro molar inferior incluso. Detalhamentos de Caso: Paciente gênero feminino, 20 anos de idade, leucoderma, sem alterações sistêmicas e psicológicas, compareceu à clínica para extração do elemento dentário 48 incluso. A paciente foi submetida à anestesia pterigomandibular sem intercorrências. Após o procedimento a paciente foi para sua casa ainda com o lábio anestesiado e acabou dormindo. Ao acordar notou que estava com o rosto e com a blusa de sangue, e ao olhar no espelho observou que havia perdido parte do lábio inferior e que provavelmente teria mastigado e engolido uma vez que ainda estava sob efeito da anestesia. A paciente procurou o serviço do Hospital onde foi submetida a um procedimento de cirúrgico pela equipe de cirurgia bucomaxilofacial e cirurgia plástica sob anestesia geral. Considerações finais: é de suma importância a explicação do cirurgião sobre o pós-operatório das cirurgias, sobre os cuidados com a anestesia local, o tempo de efeito de duração droga e os efeitos que ela pode causar enquanto se aguarda metabolização completa da solução em questão.