PURPOSE:To evaluate the effects of low intensity ultrasound on the healing process of third degree burn wounds in experimentally induced diabetic Wistar rats. METHODS:One hundred rats were divided into: control group; non-diabetic treated group; diabetic control group; diabetic treated group. The therapy was performed with a 3MHz ultrasound application, pulsed emission at 100Hz frequency, modulated at 20% with a dosage of 0.5W/cm 2 during three minutes throughout 30 days. The surgical debridement of the wound was performed once at day 2. The wounds were morphometrically, macroscopically and microscopically evaluated at 3, 7, 14, 21 and 30 days. RESULTS:The wound contraction and collagen quantification were higher in all treated groups. Macroscopically, necrosis was higher in the diabetic control group. Granulation tissue was higher in treated groups during the proliferative and remodeling phase.Microscopically, there were greater mononuclear inflammatory infiltration, angiogenesis and fibroblast quantification in treated groups during the proliferative and remodeling phases.CONCLUSIONS: therapeutic ultrasound is beneficial in the inflammatory and proliferative phases of the healing process because it controlled the necrotic tissue, increased the granulation tissue and wound contraction. However in the remodeling phase it is not beneficial because of the continued angiogenesis and a mononuclear inflammatory infiltration.

PURPOSE:To analyze the healing effects of stromal vascular fraction (SVF) application compared to wound dressing with 2% silver sulfadiazine in full thickness burn wounds in rats. METHODS:Animals were divided into two groups: 2% silver sulfadiazine group and SVF group. Both groups received occlusive bandages while the first one was treated with 2% silver sulfadiazine and the latter was treated with injections of SVF prepared from adipose tissue extracted from an animal donor. The animals were accompanied through 3, 7 and 30 days for evaluation of macroscopic, microscopic and morphometric aspects. RESULTS:On day three, a significant increase (p<0.05) of infiltration of polymorphonuclear, fibrin formation and fibroblasts migration in SVF group was observed. On the 7 th day the mononuclear infiltrate, angiogenesis, collagen and fibroblasts were significantly increased in the SVF group (p<0.05). At 30 days significantly increased collagen deposition was observed in the SVF group (p<0.05). CONCLUSION:Adipose tissue derived stromal vascular fraction injections promotes better wound repair than 2% silver sulfadiazine in the treatment of full thickness burn in rats during the evaluated experimental period.

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Objetivos: Avaliar os efeitos de um programa de hidrocinesioterapia na funcionalidade, risco de quedas e alterações musculoesqueléticas de idosas ativas participantes da Universidade Aberta à Terceira Idade da Pontifícia Universidade Católica de Goiás (UNATI PUC-GO). De forma secundária, objetivou-se correlacionar o perfil epidemiológico com a funcionalidade.Materiais e Métodos: Estudo quase experimental, com uma amostra de 60 idosas, que frequentaram a oficina FISIOÁGUA, durante quatro meses, duas vezes por semana, por cinquenta minutos. Avaliou-se a funcionalidade pelo Short Physical Performance Battery (SPPB) e o risco de quedas pelo Quick Screen Clinical Falls Risk Assessment. A análise estatística foi realizada no SPSS utilizando-se o teste de Kolmogorov-Smirnov para determinar a normalidade dos dados, teste Wilcoxon para comparação e para correlação o índice de correlação de Pearson, com nível de significância de p<0,05.Resultados: A média de idade foi de 67±6,0 anos, índice de massa corporal 28,88±6,0 kg/cm², sendo que 56,7% apresentavam Artrite/artrose e 40% Osteoporose. Foram encontradas diferenças estatisticamente significantes após a intervenção na funcionalidade (p=0,0001) e risco de quedas (p=0,0001). Ao se realizar uma análise de subgrupos, as idosas com Artrite/artrose e osteoporose após intervenção apresentaram melhora significativa na funcionalidade (p=0,0001). Observou-se uma correlação estatisticamente significante, moderada e negativa entre a idade e a velocidade da marcha pré-intervenção (r=-0,333, p=0,009). Após a intervenção (r=-0,202, p=0,122) a correlação não foi significativa.Conclusão: Observou-se que o programa de hidrocinesioterapia foi efetivo na melhora da funcionalidade, na diminuição do risco de quedas e alterações musculoesqueléticas de idosas ativas que apresentavam ou não artrite/ artrose e osteoporose.

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