Ag 2 (9-aca) 2 ] (1) (9-acaH = 9-anthracenecarboxylic acid) reacts with a series of imidazoles to give [Ag(imidH) The mononuclear complex 3, hexanuclear 4-6, and polymeric 7, were all characterised using X-ray crystallography. While many of the complexes possess excellent in vitro antifungal and antibacterial activities they are, unanimously, more effective against fungal cells. The insect, Galleria mellonella, can survive high doses of the Ag(I) complexes administered in vivo, and a number of the complexes offer significant protection to larvae infected with a lethal dose of pathogenic Candida albicans cells. † Electronic supplementary information (ESI) available. CCDC reference numbers 782886-782890 (X-ray supplementary data for [Ag-(imidH) 2.3 (CH 3 CN) 0.7 ](9-aca) (3), [Ag 6 (imidH) 4 (9-aca) 6 (MeOH) 2 ] (4), {[Ag(1-Me-imid) 2 ] 2 [Ag 4 (9-aca) 6 ]} (5), {[Ag(1-Bu-imid) 2 ] 2 [Ag 4 (9aca) 6 ]} (6) and [Ag(apim)](9-aca)•H 2 O (7)). For ESI and crystallographic data in CIF or other electronic format see

a b s t r a c t[Ag 2 (9-aca) 2 ] (9-acaH = 9-anthracenecarboxylic acid) interacts with DMSO and a selection of substituted imidazoles giving [Ag 4 (DMSO) 4 (9-aca) 4 In the carboxylate/imidazole complexes 2-4, the imidazole ligand is in the neutral form, whilst in complexes 6-9 the imidazolate ligand is deprotonated and no carboxylate ligand is present. Attempted recrystallization of 4 from EtOH gives the metal-free, imidazolium salt, 2-Mebenz-imH 2 )(9-aca)ÁH 2 O (5). The X-ray crystal structures of complexes 1 and 2 and the salt 5 were determined. Antimicrobial screening showed that the Ag(I) complexes were substantially more active against the fungus Candida albicans than the bacterial species, methicillin-resistant Staphylococcus aureus (MRSA) and Escherichia coli. Some of the complexes offer a good prognosis for Galleria mellonella (larvae of the greater wax moth) infected with a lethal dose of C. albicans cells.

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Two series (4,6-dihydro and 4,6-dimethyl) of syn-bimanes [1,5-diazabicyclo[3.3.0]octa-3,6-diene-2,8-diones] have been converted to acetylene and diacetylene derivatives. Their chemical and photophysical properties are reported. The 3-(and 6-)iodo (diiodo) derivatives are the best choices for Stille or Heck condensations with acetylenes or acrylates. Desilylation of (trimethylsilyl)acetylenes is best carried out with silver nitrate followed by lithium bromide. The acetylenes and diacetylenes are quite stable and highly fluorescent and represent candidate units for incorporation into polymers.

Bimanes. 14. Synthesis and Properties of 4,6-Bis(carboalkoxy)-l,5-diazabicyclo[3.3.0]octa-3,6-diene-2,8-diones [4,6-Bis(carboalkoxy)-9,10-dioxa-syn-bimanes]. Preparation of the Parent syn -Bimane, syn -(Hydrogen,hydrogen)bimane