Purpose To describe a case of keratitis caused by the Gram-negative Escherichia coli, treated with UVA-riboflavin cross linking. Methods Case report. Results A 78-year-old woman with diabetes presented with a 1-week history of pain, photophobia, foreign body sensation, and lacrimation in the right eye. The patient underwent topical and systemic antimicrobial therapy, without improvement. The authors treated the patient with riboflavin and corneal UVA crosslinking, with the aim to promote healing of the ulceration. One day after the procedure, the corneal ulceration was covered by cicatricial tissue, and the patient reported a significant improvement in symptoms. One month after the treatment, corneal edema was almost completely resolved, corneal ulceration was healed, and the painful symptoms of the patient had disappeared. Conclusions UVA-riboflavin crosslinking can be useful for the treatment of corneal ulceration unresponsive to medical treatment.

Multifocal electroretinogram can be useful to predict functional prognosis in patients with diabetes who underwent vitrectomy for diabetic macular edema.

Keratoconus associated with myelinated retinal nerve fibers is not frequent and the relationship between the two pathologies is difficult to explain, therefore studies and further investigation are required. The etiology of each condition may suggest the role of genetic factors. Follow-up is important to evaluate the progression of keratoconus and myelination. Here we describe the unusual coexistence of keratoconus and ipsilateral myelinated retinal nerve fiber layer and, for the first time, the corneal cross-linking treatment in this condition.

Purpose To report transient vitreomacular traction (VMT) syndrome following acute blunt trauma associated with incomplete posterior vitreous detachment. Methods The authors present the analysis of 2 eyes of consecutive patients with acute VMT following mild blunt trauma. Both patients reported a sudden decrease in visual acuity and metamorphopsia. Spectral domain optical coherence tomography (OCT) images showed typical VMT syndrome. Results The development of complete posterior vitreous detachment demonstrated by OCT, after 15 and 30 days, respectively, was associated with complete resolution of symptoms and complete recovery of foveal architecture. Conclusions The authors report spontaneous resolution of VMT associated with blunt trauma. As spontaneous resolution may occur in some eyes with VMT following traumatic acute incomplete vitreous detachment, a period of observation may be considered prior to vitrectomy. Spectral domain OCT is a useful tool in following the evolution of these patients.

<h4>ABSTRACT</h4> <p>Tubulointerstitial nephritis and uveitis syndrome is likely underdiagnosed. A 13-year-old girl with no significant medical history had photophobia, ocular pain, and decreased visual acuity. Bilateral papilledema was present. Renal biopsy revealed interstitial nephritis. Immunosuppressive therapy was added (3 mg/kg/d of cyclosporine). One year later, visual acuity was 20/20 and findings were normal on ocular examination and laboratory tests.</p> <p><cite>J Pediatr Ophthalmol Strabismus</cite> 2006;43:241-243.</p> <h4>AUTHORS</h4> <p>The authors are from the Dipartimento di Oftalmologia e Otorinolaringoiatria, Division of Ophthalmology, University of Bari, Bari, Italy.</p> <p>Originally submitted November 17, 2004.</p> <p>Accepted for publication May 13, 2005.</p> <p>Address reprint requests to Marco Leozappa, MD, U. O. Oftalmologia, Policlinico di Bari, P.zza Giulio Cesare 1, 70124, Bari, Italy.</p>