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Objective: To identify the pattern of spatial distribution and temporal evolution of leprosy, taking into account the clinical, demographic and territorial aspects of Vila Santo Antônio do Prata, a municipality considered to be hyperendemic, in the state of Pará from 2003 to 2013. Methods: This is a ecological, observational and retrospective study. The study was the former colony of leprosy, now known as the Vila de Santo Antônio do Prata. Results: High rates of detection of new cases of leprosy were observed with a hyperendemic detection coefficient from 2003 to 2009. The spatial distribution of total cases of leprosy presents a pattern of distribution with several outbreaks, in which the incidence of multibacillary cases. The trend estimates for 2020 has shown that Brazil will maintain the index in slow and gradual reduction, while the state of Pará will continue with high rates of hyperendemicity and the municipality of Igarapé-Açu will surpass the North region. Conclusion: It is suggested that there is an active transmission dynamic in Vila Santo Antônio do Prata area evaluated with the need for constant monitoring of new cases of leprosy.

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