Objective To compare the efficacy of osteoprogenitors in fibrin glue to fibrin glue alone in bone healing of surgically induced ostectomies of the fourth metacarpal bones in an equine model. Study Design Experimental. Animals Adult horses (n = 10). Methods Segmental ostectomies of the 4th metacarpal bone (MC4) were performed bilaterally in 10 horses. There was 1 treatment and 1 control limb in each horse. Bone defects were randomly injected with either fibrin glue and osteoprogenitor cells or fibrin glue alone. Radiography was performed every week until the study endpoint at 12 weeks. After euthanasia, bone healing was evaluated using radiography and histology. Analysis of radiographic data was conducted using a linear‐mixed model. Analysis of histologic data was conducted using a general linear model. Statistical significance was set at P < .05. Results Radiographic grayscale data as a measure of bone healing revealed no significant difference between treatment and control limbs. Radiographic scoring results also showed that the treatment effect was not significant. Histologic analysis was consistent with radiographic analysis showing no significant difference between the area of bone present in treatment and control limbs. Conclusion Injection of periosteal‐derived osteoprogenitors in a fibrin glue carrier into surgically created ostectomies of MC4 does not accelerate bone healing when compared with fibrin glue alone.

Cecal bypass via side-to-side ileocolic anastomosis without ileal transection seemed to offer 2 potential advantages over traditional surgical techniques for treating this condition. The risk of abdominal contamination was far less than with techniques in which the colotomy is needed to enable resection of the cecum or techniques in which the ileum is transected. Also, it was technically simpler to perform because there was no need to transect the ileum, oversew the ileal stump, perform cecal resection, or close the mesenteric space created by relocating the jejunal stump to the right ventral colon.

Results suggested that use of TUS for gastric fluid volume estimation is a potentially useful technique.

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A two-year-old Arabian filly was referred with symptons of colic. Clinical examination revealed signs associated with endotoxemia. Ultrasonographic examination of the abdomen demonstrated severe distention of the stomach and distended loops of small intestine with reduced motility. With nasogastric intubation, eight liters of hemorrhagic reflux were retrieved. Gastroscopic examination showed a severe degree of gastric ulceration scored as equine gastric ulcer syndrome (EGUS) grade IV. Based on these findings, EGUS and gastroduodenitis (GD) were diagnosed. Initially, the horse was treated using parenteral pantoprazole, which was supplemented by adding enteral ranitidine and sucralfate when the horse ceased refluxing. The horse was discharged eleven days after presentation with a 75%-healing of the gastric ulcers. A control gastroscopic examination was performed thirty days after discharge showing a 90%-healing (EGUS Grade I). To the authors’ knowledge, this is the first case report in which pantoprazole in combination with ranitidine and sucralfate has been used to treat a severe degree of gastric ulceration.