Our results suggest that PONV treatment with ondansetron could be improved by basic, widely available and inexpensive PCR-RFLP genetic tests.

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As so ci ate Ed i tor: Leszek KrzemiñskiThe Staré Mìsto Belt (SMB) in the Cen tral Sudetes forms a Variscan tec tonic bound ary zone that is lo cated be tween the Saxothuringian and Brunovistulian ter ranes of the Bo he mian Mas sif. The three thrust-bounded up per, mid dle and lower lithotectonic units of the SMB are com posed of metasedimentary and Late Cam brian meta vol can ic rocks. A new LA-ICPMS zir con geo chron ol ogy sup ported by zir con typology stud ies of the mica schists of the up per unit and the migmatitic paragneisses of the mid dle unit pro vides new in sights into the prov e nance and evo lu tion of the SMB. Our new data were obtained from metasedimentary rocks and com pared to the pre vi ously pub lished zir con ages of the SMB meta vol can ic rocks. The re sults in di cate that the metasedimentary and bi modal meta vol can ic rocks in the sep a rate lithotectonic units of the SMB orig i nally formed Late Cam brian vol cano-sed i men tary suc ces sions. The source ar eas of the sed i men tary bas ins stud ied were dom i nated by Neoproterozoic and Paleoproterozoic crys tal line rocks that were pre sum ably lo cated near the West Af rican Craton of Gond wana. A com par i son of the de tri tal age spec tra ob tained with those pre vi ously pub lished from the re gion in di cates a strong as so ci a tion of the en tire SMB with the Saxothuringian terrane of the Bo he mian Mas sif. Dur ing par tial melting of the metasedimentary rocks of the mid dle unit of the SMB, Cam brian and older zir con grains were af fected by solid-state trans for ma tions that caused par tial re set ting of the U-Pb dates, changes in in ter nal zir con tex tures and re duc tions in Th/U ra tios.

<p>Late Proterozoic to Early Palaeozoic metavolcano-sedimentary successions are important components of the Variscan massifs of Europe. Felsic and mafic metavolcanic rocks with Cambro-Ordovician protolith ages also occurs in the Staré Město Belt (SMB) in the Central Sudetes (Czech Republic, Poland) (e.g. Kröner et al. 2000). The SMB is the NNW-trending fold-and-thrust belt that forms the eastern margin of the Saxothuringian Zone of the Bohemian Massif. To constrain timing and geodynamic setting of the volcanism recorded in that part of the Saxothuringia, the whole rock geochemistry, zircon trace element geochemistry and U-Pb zircon geochronology of metabasalts, metagabbros and acid metavolcanites of the SMB were carried out.</p><p>Field and petrographic studies show that bimodal association in the SMB is mainly expressed by alternating layers of fine-grained amphibolites composed of Amp, Pl and Px and fine- and medium-grained acid metavolcanites composed of Qz, Pl, Kfs, Grt, Bt and Ms. Such close relationships between felsic and mafic meta-volcanic rocks suggest their common origin. Whole-rock geochemistry data suggest, however, a diversity both in the chemical composition and tectonic environments of formation of their igneous protoliths. Magmatic precursors of the amphibolites were tholeiitic and calc-alkaline basalts, andesitic basalts and andesites that were derived either from MORB, BABB, volcanic arc or within-plate magmas. The acid metavolcanites originated from rhyolites and dacites belonging to tholeiite, calc and calc-alkaline series. Geotectonic diagrams suggest that the felsic magmas were formed most likely in island arc or continental arc environments.</p><p>New LA-ICPMS zircon dating of two metadetrital rocks of the SMB revealed the predominance of Neoproterozoic-Cambrian and Palaeoproterozoic age clusters, characteristic for rocks of the Saxothuringian Zone. Zircon dating of four samples of acid metavolcanites, two samples of metabasalts and one sample of metagabbro confirmed that their igneous protoliths crystalized at the same time, at ca. 495-500 Ma. Trace elements in zircons were analyzed in all metavolcanic samples. Range of values of Nb/Yb = 0.001-0.1, U/Yb = 0.1-10 and Y = 25-6993 ppm are observed in both types of rocks and together indicate a contribution of continental crust in the SMB volcanites. Their values plotted on geotectonic classification diagrams of Grimes et al. (2015) suggest a continental arc setting for the whole Late Cambrian bimodal volcanism in the easternmost part of the Saxothuringian Zone.</p><p>The research was financed from the grant of the National Science Center, Poland No. 2018/29/B/ST10/01120.</p><p> </p><p>References:</p><p>Grimes, C.B., Wooden, J.L., Cheadle, M.J., John, B.E., 2015.  “Fingerprinting” tectono-magmatic provenance using trace elements in igneous zircon. Contrib Mineral Petrol 170, 46.</p><p>Kröner, A., Štipská, P., Schulmann, K., Jaeckel, P., 2000. Chronological constraints on the pre-Variscan evolution of the northeastern margin of the Bohemian Massif, Czech Republic. In: Franke, W., Haak, V., Oncken, O., Tanner, D. (Eds.), Orogenic Processes: Quantification and Modelling in the Variscan Belt. Geological Society, London, Special Publications 179, pp. 175–197.</p>