An outbreak of Bordetella bronchiseptica pneumonia occurred in a breeding colony of common marmosets (Callithrix jacchus). 16 animals, all except one under 12 months of age, died suddenly. Extensive lesions of pneumonia and pleurisy were found at necropsy and B. bronchiseptica was isolated from the nasopharynx, trachea and lungs. Older animals had only a mild rhinitis. Colonization of the nasal mucosa occurred in 71 of 156 marmosets.
Most dogs in a closed breeding unit were shown to be asymptomatic excretors of campylobacter organisms by eight weeks old. Increasing serum antibody levels, which were correlated with the excretion of organisms, were demonstrated in the puppies and serum antibodies were also demonstrated in adult dogs. The significance of these findings with respect to the pathogenicity of campylobacter in dogs and their zoonotic implications are discussed.
Facial abscesses in a colony of common marmosets were found to be caused by abscessation of an upper canine tooth root. Trauma to the upper canine, resulting in exposure of the pulp cavity, was thought to be the mode of infection. Radiography was the most useful diagnostic aid in establishing the nature and extent of the lesion. Antibiotic therapy alone was inadequate, and provision of drainage by extracting the tooth, in conjunction with antibiotics, proved the most effective treatment.
Pulmonary interstitial fibrosis commenced as focal proliferation of fibroblasts and accumulation of macrophages in interalveolar septa and was followed by deposition of excess collagen. Epithelium of airways and alveoli remained normal. Perivascular nodules of lymphoid tissues which developed in the lungs of many older animals had a high mitotic rate, but the lymphocytes were morphologically normal. Micro-organisms were not observed in the lungs of any animal.
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