Stroke has become the second leading cause of death and the third leading disability globally caused by several factors, such as hypertension, diabetes Mellitus, atrial fibrillation, and cholesterol. DSA (Digital Subtraction Angiography) has been the gold standard for diagnosing abnormalities in cerebrovascular, such as aneurysms and malformation artery and vena. Cerebral DSA is a safe procedure and has the advantage that intervention procedures such as stent insertion or thrombectomy can be performed immediately after angiography. This research is intended to find the characteristic of a stroke patient treated with Digital Subtraction Angiography. The design used in the study is retrospective with a medical record of a stroke ischemic patient who was treated with Digital Subtraction Angiography at RSUD CAM Bekasi from August 2020 - to June 2021. The sampling technique of this study was taken using total sampling techniques; namely, the entire population that the researcher had determined was a research sample. Forty-nine patients are used as the research sample according to the inclusive criteria. As a result, it has been found that the demographic in which Digital Subtraction Angiography has been utilized is 41-59 years old (61.2%), of which 65.3% of them are male patients. Based on their education, most of them come from strata 1, sitting at 61.2%, and their occupation is commercial workers, sitting at 26.5%. Risk factors that come with Digital Subtraction Angiography are hypertension (91.8%) and vertigo symptoms (55.1%). For motoric patients, 12.3% have seen improvements. Meanwhile, according to the National Institute of Health Stroke Scale, 46.9% have seen improvements. Digital Subtraction Angiography results show that 53.1% of ischemic stroke patients have improved. Key words: Stroke Ischemic, Digital Subtraction Angiography.

Non-communicable diseases such as ischemic heart disease, stroke, chronic obstructive pulmonary disease, lung cancer, Alzheimer, diabetes melitus, and kidney disease are leading causes of death in the world. There are many risk factors which can contribute to non-communicable diseases such as dietary. Vegetable consumption such as tomato may lower risk factors to non-communicable diseases because of its active ingredient, lycopene, retinol, alpha tomatine, and tomatidine. In this study, authors aim to explain the mechanism of tomato’s active compound in lowering risk factors of non-communicable disease based on biomarker found on each disease collected from recent epidemiological, in silico, in vitro, and in vivo researches. Lycopene and retinol have proven in reducing ischemic heart disease and stroke because of its anti-atherogenic properties and anti-inflammatory effect. Anti-oxidative and anti-inflammatory effect of lycopene also proven in lowering risk factors of chronic obstructive pulmonary diseases by modulate reverse cholesterol transport, so cholesterol homeostasis is created. In lung cancer, lycopene and other bioactive compound such as α-tomatine and tomatidine also have an anti-proliferative effect by interacting with Epidermal growth factor receptor (EGFR). Its ability to reduce the final product of lipid peroxidation level makes lycopene lower Alzheimer risk factor. There is much more function of tomato’s active coumpound although pure tomato has contradictive effect on some disease.