Evidence for an unidentified steroid in a child with apparent mineralocorticoid hypertension. J Clin Endocrinol Metab 1977;44:924-33. 4 Case report A girl, aged 2-years at the time of this report, had been observed since birth. Her mother was known to have a sporadic form of HR with severe bone abnormalities (osteomalacia) and dwarfism, and had been treated during infancy with combined phosphates and vitamin D3 without any improvement. The pregnancy was normal, and a caesarean section was performed for maternal indications.Our patient's birthweight was 3-3 kg and her length was 52 cm. A physical examination at age 2 months showed her to be normal-weight and height at the 25th centile. Laboratory investigations at that time found the following: hypophosphataemia-phosphate 1 13 mmol/l (3 5 mg/dl), normal range for our laboratory I 29-2-09 mmol/l; normal serum calcium 2-23 mmol/l (9-2 mg/dl), normal range 2-1-2-6 mmol/l; raised alkaline phosphatase-56 KA units, normal range 7-5-32*5 KA units; hypocalciuria-0 0365 mmol/kg/24 hours (1 46 mg/kg/24 hours); hyperphosphaturia-45-54 mmol/l 73m2/24 hours (1 41 mg/ 173m2/24 hours); and a reduction in renal tubular reabsorption of phosphate-60 %.

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