Resumen En la comunidad médica existen opiniones muy dispares frente al aborto. Nos proponemos analizar las premisas filosóficas que enmarcan la opinión de los médicos respecto a la legalización del aborto y corroborar cómo varían según la pertenencia generacional de los profesionales; así como establecer qué rol juega la objeción de conciencia para lograr un equilibrio ante la variedad de posturas existentes. Se realizaron entrevistas a médicos y a estudiantes de medicina interrogando si les parecía correcto o no legalizar el aborto y las razones en las cuales basaban sus posturas . Los médicos más jóvenes fueron quienes se mostraron a favor de la legalización en mayor proporción con argumentos brindados con una perspectiva en salud pública. Ante tan variadas posturas e idiosincrasias que conviven en el ámbito médico, la objeción de conciencia se erige como un instrumento legal necesario para proteger la integridad moral de cada persona.
Background
It has been described that Trypanosoma cruzi is capable of promoting metabolic disturbances currently considered as cardiovascular risk factors. Moreover, it has been observed that the protozoa can remain in adipose tissue and alter its immune endocrine functions. The aim of this study was to characterize the thickness of epicardial adipose tissue (EAT) in patients with chronic Chagas disease (CCD) concerning their cardiovascular metabolic risk profile compared with those without CCD.
Methods
A cross-sectional study was performed including T. cruzi seropositive individuals categorized according to a standard CCD classification and a matched seronegative control group. Complete clinical examination, metabolic laboratory tests and transthoracic echocardiography to assess cardiac function and to quantify EAT were performed.
Results
Fifty-five individuals aged 46.7±11.9 y, 34 with CCD and 21 in the control group, were included. The CCD group presented higher EAT thickness in relation to controls (4.54±1.28 vs 3.22±0.99 mm; p=0.001), which was significantly associated with the presence of insulin resistance (OR=3, 95% CI 1.58 to 5.73; p<0.001). This group presented lower levels of plasmatic adiponectin than controls, especially in those patients with EAT ≥4.5 mm (p=0.005) who also presented with heart failure more frequently (p=0.01).
Conclusion
In patients with CCD, a higher EAT thickness is observed and is associated with an increased metabolic risk profile indicated mainly by insulin resistance.
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