Introduction: Congenital syphilis is an infectious disease responsible for affecting the lives of thousands of Brazilian women and that, perceptibly, has been growing, even with the reality of underreporting in the country, due to the low quality of health care for such women. Objective: To evaluate the epidemiological profile of congenital syphilis in the state of Pará from 2010 to 2021. Methods: Descriptive and cross-sectional research of notified and confirmed cases of congenital syphilis, through the National System of Notifiable Diseases (SINAN). The variables were analyzed: health region, education, gender, age group, race, the performance of prenatal care, and treatment of the maternal partner. Results: Of the total of 7,595 cases, the highest occurrence was in the year 2019 (n = 945). Concepts up to six days old were the most affected age group (95.78%). Regarding the epidemiological characteristics of the genitor, the predominance was of brown color (82.57%) and who had prenatal care (84.6%). Untreated sexual partners totaled 4,663 (61.4%), approximately four times more than treated partners, 1,365 (18.0%). Conclusion: The study showed a significant increase in cases of the disease in the state of Pará, being the group of brown mothers with low education the most affected and with previously untreated partners. Moreover, it was evident that even with prenatal care the infection developed, confirming the fragile care system offered to pregnant women. Thus, this study contributes to helping the authorities in the creation and improvement of effective measures, since the relevant obstacles were addressed.
Actinobacteria are important components of the microbial population in most soils and are widely distributed and abundant, especially in the rhizosphere. The phylum Actinobacteria, particularly the genus Streptomyces, is recognized for its potential to produce a vast quantity of secondary metabolites, among which there are bioactive compounds used as antibiotics. The present study sought to isolate and identify actinobacteria from secondary forest rhizosphere in the region of Igarapé-Açu and to evaluate the biotechnological potential of these strains for the production of antimicrobials. Thirty rhizospheric soil samples were collected, pre-treated and seeded on Czapeck Dox and Saboraud Dextrose Agar. The methodology applied consisted of phenotypic analysis, morphological (macroscopic and microscopic) and biochemical characterization. In addition, the isolated strains were submitted to antimicrobial potential evaluation tests in order to verify if they were effective in inhibiting the growth of the multi-resistant pathogenic bacteria Escherichia coli and Klebsiella pneumoniae. We identified 18 strains of actinobacteria with the following presumptive genera: Streptomyces, Nocardia and Actinoplanes. Among the 18 strains, 10 were able to form at least a halo of inhibition against one of the pathogenic bacteria.
As diversas áreas do desenvolvimento e seus conceitos [livro eletrônico] / organização Fabrico Custódio de Moura Gonçalves. --Curitiba, PR : Seven Events, 2022. PDF Vários autores. Bibliografia. ISBN 978-65-997403-7-4 1. Aptidão física 2. Atividade física -Aspectos fisiológicos 3. Desenvolvimento humano 4. Educação física 5. Esportes -Aspectos fisiológicos I. Gonçalves,
The soil is a propitious place for the development of decomposer microrganisms, mainly fungi and bacteria. The soil colonization from those organisms occurs in places with great availability of organic matter, like the rhizosphere and animal breeding soils, like poultry farming. Among the microrganisms present in this type of soil, there are the actinomicetes, which belong to phylum of gram-positive bacteria with filamentous estructures that constitute aerial mycelia. The objective of this article was to isolate, bioprospect, characterize morfologically and biochemically and to assess the antimicrobial potential of strains of bacterias from chicken breeding in the city of Igarapé-Açu, Pará. As a result, bacterial colonies with variable features that indicate the genus Actinobacteria were found, amongst them one showed potential antibacterial against a strain of Klebsiella pneumoniae
Actinobacteria form a heterogeneous group of Gram-positive bacteria that have a great morphological and metabolic variety, are microorganisms with great biotechnological potential for the production of several substances of industrial and pharmaceutical interest, being considered the main source of antibiotics. Due to the increase in the occurrence of bacteria that are multiresistant to antibiotics used in clinical and hospital routine, the need to discover new substances with antibiotic capacity becomes evident. Thus, studies that assess the diversity and variety, composition and properties of metabolites produced by bacterial species present in cultivated soils are important and necessary. This work aimed to investigate the occurrence of actinobacteria in rhizosphere soils of areas cultivated with cassava (Manihot esculenta) and black pepper (Piper nigrum) in the city of Igarapé Açu -Pará, Brazil, to assess their potential as producers of antimicrobial substances. This is an analytical descriptive, experimental study that performs a microbiological analysis of soil samples. With great morphological diversity, 21 different bacteria were isolated, all with characteristics of actinobacteria. As a result, strains of actinobacteria with variable colonial characteristics were isolated, microscopically characterized as isolated and chained Gram-positive bacilli. Among the isolates, 8 strains were able to inhibit the growth of Escherichia coli and Klebsiella pneumoniae compared to in vitro. It emphasizes the need for more research aimed at the microbiology of Amazonian soils, due to the diversity of bacteria of biotechnological importance that can significantly contribute to the production of new antibiotics, thus generating a positive expectation in the fight against infections.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.