Objective
To study a rare case of spontaneous ovarian hyperstimulation syndrome in a naturally conceived pregnancy associated with overt hypothyroidism.
Design
Case report.
Setting
Endocrinology private practice.
Patient(s)
A 32-year-old woman who was 13 weeks pregnant with bilaterally enlarged ovaries presumed to be secondary to hypothyroidism.
Intervention(s)
Administration of levothyroxine and titration of the dose.
Main Outcome Measure(s)
Regression of signs and symptoms of spontaneous ovarian hyperstimulation syndrome after 12 weeks of therapy.
Result(s)
The patient was diagnosed with severe hypothyroidism, as confirmed by her elevated thyroid-stimulating hormone level. Ultrasound evaluation revealed ovarian enlargement secondary to multiple contiguous cysts with anechoic content. The patient was administered levothyroxine 175 μg/day. Results of hormonal studies demonstrated thyroid function normality at week 12 after treatment. Incomplete regression of ovarian cysts was also noticed within this period. At week 37, the patient developed preeclampsia, and cesarean delivery was recommended. An 8-month postpartum ultrasound evaluation revealed complete regression of the cysts.
Conclusion(s)
Spontaneous ovarian hyperstimulation syndrome secondary to hypothyroidism may be the cause of ovarian enlargement, and levothyroxine replacement seems an appropriate primary therapeutic option. Proper endocrinological assessment of patients is recommended as it may avoid unfavorable outcomes.
RESUMOObjetivo: Analisar a prevalência das doenças endocrinometabólicas no ambulatório do Hospital Universitário Ciências Médicas de Minas Gerais (HUCM). Métodos: Trata-se de estudo observacional e transversal realizado através da análise de prontuários de pacientes que foram atendidos no ambulatório de endocrinologia do HUCM, durante os meses de fevereiro de 2018 a dezembro de 2019. A amostra foi por conveniência, o tamanho da amostra de 531 prontuários e a amostra final de 216 pacientes. Os dados obtidos foram analisados por uma análise descritiva. O estudo foi aprovado pelo Comitê de Ética em Pesquisa. Resultados: Foi estabelecida a prevalência das doenças endócrino metabólicas no ambulatório HUCM, sendo o Diabetes mellitus não-insulino-dependente a doença mais prevalente no período estudado, seguida da Obesidade e do Hipotireoidismo. Conclusão: Conclui-se que analisar a prevalência das doenças endocrinometabólicas e o seu perfil de acometimento é importante para a melhor condução dos casos e alocação apropriada de recursos.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.