Active and passive intervals (AI, PI) between exercise series promote different hemodynamic responses; however, the impact of these intervals on the blood pressure response has not yet been investigated. The objective of this study was to compare the impact of AIs and PIs during resistance exercises with the magnitude of postexercise hypotension (PEH). Elderly hypertensive women (n = 21, 61.2 ± 2 years of age) completed 4 sessions for upper or lower limbs with AI or PI (3 sets, 15 repetitions, 60% load of 15 repetition maximum (RM), and an interval of 90 seconds between sets). Blood pressure was measured 10 minutes before and at 10, 20, 30, 40, and 50 minutes after the exercise sessions. The heart rate at the end of each AI was always significantly higher than that after the PI, but the perceived exertion as measured by the Perceived Exertion Scale (OMNI-RPE) was similar to that of PI exercise protocols. In the lower limb exercises, AI resulted in significantly and consistently higher PEH than in exercises with PI for both systolic (from 20 minutes postexercise) and diastolic (from 10 minutes postexercise) pressures. The upper limb exercises promoted much more discrete PEH in relation to the lower limb exercises, given that the AI promoted significantly higher PEH relative to the PI protocols, but only for systolic PEH and only from 30 minutes postexercise. This is the first time that AIs between sets in a session of resistance exercises have been shown to be a highly effective methodological strategy to increase PEH in elderly hypertensive women.

Behavioral disorders affect most diabetic patients and Zinc (Zn) has been used among adjuvant therapies for involvement in the etiology of depression and anxiety, however, the results are still controversial. The objective of this study was to compare the antidepressant, anxiolytic and neuroprotective activity of the supplementation of two Zn compounds in an animal model of Diabetes Mellitus type 1 (DM1). Thirty-eight (38) adult rats were randomized into four groups: Control (C; n = 8); Diabetic (D; n = 10); Diabetic Zn Sulfate Supplement (DSZ; n = 10) and Diabetic Zn Gluconate Supplement (DGZ; n = 10). The DSZ group received Zn sulfate supplementation and the DGZ group received Zn gluconate supplementation at a dose of 15 mg/kg for 4 weeks. Data (mean ±SEM) were analyzed by the Mann-Whitney test with a significance level of p < 0.05. The results indicate that Zn gluconate supplementation in diabetic animals presented an antidepressant effect demonstrated through the results obtained in the Forced Swim Test, and neuroprotective effect by attenuating alterations in the cerebral cortex; while Zn sulfate supplementation in diabetic animals showed an anxiolytic effect demonstrated by the results obtained in the open field test and the elevated plus maze test. Considering the set of results, supplementation with both zinc compounds showed neurobehavioral benefits in diabetic animals with different effects depending on the type of anion associated with Zn.

a b s t r a c tEffects of treatment with the bark flour of Passiflora edulis Sims, Passifloraceae, were evaluated. Adult male Wistar rats were treated for 30 days (130 mg/kg, p.o.) with the albedo flour, flavedo and full bark of P. edulis, corresponding to albedo associated with flavedo. Behavioral response observed after treatment with bark flour P. edulis showed sedative effects by the reduction of exploratory activity and increased duration of immobility in the open field test for the group of animals that received the albedo flour associated with the flavedo. Sedative effects were observed in the absence of motor incoordination or muscle relaxation. Food intake of experimental animals was not changed, but the weight gain was decreased both in animals that received only albedo flour, and in those who received the full bark flour. The full bark flour of Passiflora showed sedative effects, without anxiolytic effect detectable and muscle relaxation or motor incoordination, and reduces body weight gain.

There is a high prevalence of cardiovascular risk factors in a population of RTRs, and there is increased risk for MACE and death. Accurate risk prediction is important for physician decision support and patient education, promoting improved cardiovascular health of RTRs, and thus prolonging the survival of both patients and graft.

Serum chromium deficiency is frequent in candidates for bariatric surgery and is associated with total cholesterol and triglyceride concentrations. Early nutritional interventions are needed to reduce nutritional deficiencies and improve the lipid profile of these patients.