This review provides a synthesis of the last ten years of research on nanodelivery systems used for the delivery of essential oils (EOs), as well as their potential as a viable alternative to antibiotics in human and veterinary therapy. The use of essential oils alone in therapy is not always possible due to several limitations but nanodelivery systems seem to be able to overcome these issues. The choice of the essential oil, as well as the choice of the nanodelivery system influences the therapeutic efficacy obtained. While several studies on the characterization of EOs exist, this review assesses the characteristics of the nanomaterials used for the delivery of essential oils, as well as impact on the functionality of nanodelivered essential oils, and successful applications. Two classes of delivery systems stand out: polymeric nanoparticles (NPs) including chitosan, cellulose, zein, sodium alginate, and poly(lactic-co-glycolic) acid (PLGA), and lipidic NPs including nanostructured lipid carriers, solid lipid NPs, nanoemulsions, liposomes, and niosomes. While the advantages and disadvantages of these delivery systems and information on stability, release, and efficacy of the nanodelivered EOs are covered in the literature as presented in this review, essential information, such as the speed of emergence of a potential bacteria resistance to these new systems, or dosages for each type of infection and for each animal species or humans is still missing today. Therefore, more quantitative and
in vivo
studies should be conducted before the adoption of EOs loaded NPs as an alternative to antibiotics, where appropriate.
Summary
Aspen wood (Populus tremula) as sawdust was chemically modified through a two-step procedure: esterification
with maleic anhydride and subsequent oligoesterification with glycidyl methacrylate and maleic
anhydride. Chemical analyses and infra-red spectroscopy revealed the differences in the chemical
composition and structure of wood as a result of this treatment. These changes were also reflected by a
hygroscopicity test and thermal analyses such as thermogravimetry and thermomechanical analysis. The
esterified wood showed an increased hygroscopicity and a decreased thermal stability compared to
unmodified wood. In contrast, the oligoesterified wood demonstrated a reduced hygroscopicity and a
comparable thermal stability up to about 200°C. The thermomechanical analysis of oligoesterified wood
clearly showed a significant softening phenomenon in the range 80–140°C, a direct evidence of the thermoplastic
properties gained by this chemical modification.
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