Six additional 4-phenylcoumarins have been isolated from the MeOH extract of the bark of Exostema caribaeum. Their structures were determined by physical and chemical methods as 4'-5'-dihydroxy-7-methoxy-4-phenyl-5,2'-oxidocoumarin [1], 5,7,4'-trimethoxy-4-phenylcoumarin [2], 5,3'-dihydroxy-7,4'-dimethoxy-4-phenylcoumarin [3], 5-O-beta-D-galactopyranosyl-7,4'-dimethoxy-4-phenylcoumarin [6], 5-O-beta-D-glucopyranosyl-3',4'-dihydroxy-7-methoxy-4-phenylcoumarin+ ++ [7], and 5-O-(6"-acetyl)-beta-D-galactopyranosyl-3', 4'-dihydroxy-7-methoxy-4-phenylcoumarin [9]. The last four compounds are new natural products.
Rickettsia akari is the causative agent of rickettsialpox, a primarily urban mite-borne rickettsiosis that is encountered in the United States and in a few countries around the world. Its vector is the mite Liponyssoides sanguineus, which is found on rats and mice, which serve as reservoirs for the disease. In this work we report a severe animal case of R. akari infection with two unusual features: R. akari was found in a dog, and its potential vector was a tick.
<p>El presente artículo es un recorrido por la biblioteca de Fray Cristóbal de Torres, lector del siglo XVII en la Nueva Granada, Arzobispo de Santafé de Bogotá y fundador del Colegio Mayor de Nuestra Señora del Rosario. En él se analiza la naturaleza de dicha biblioteca en comparación con otras de la época, así como aspectos relacionados con la circulación de saberes en España y América a partir del análisis de los textos donados por el Arzobispo al Colegio Mayor del Rosario. De igual manera, el artículo permite sacar conclusiones sobre las condiciones de la educación en la Nueva Granada del siglo XVII.</p>
Por ejemplo, ministerios de cooperación, agencias oficiales de cooperación para el desarrollo, la Organización para la Cooperación y el Desarrollo Económico, OCDE y el Comité para la Asistencia al Desarrollo, CAD, entre otros. 3En estos años se destinó solamente el 0.3 % de PNB a AOD.
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