Background: The objective of this review was to evaluate the medicinal potential of Morus alba leaves on the control of type 2 diabetes mellitus (DM2). The research question was: what is the therapeutic potential of Morus alba leaves for the control of DM2? Methods: This systematic review was based on the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. The included studies were extracted from Scopus, Pubmed, ScienceDirect, Scielo, and Google Scholar; January 2015 to July 2021. Key search terms were MeSH and DeCS: Morus alba, mulberry, hypoglycemic agent. The inclusion criteria were: studies in rats administered Morus alba leaf extracts; studies that included the dimensions of lipidemia and glycemia; studies that included indicators such as fasting glucose, postprandial glucose, glycosylated hemoglobin, triglycerides, low-density lipoproteins, total cholesterol, and insulin resistance. Exclusion criteria: studies in which Morus alba leaves were administered with other plants; studies with other parts of the Morus alba plant; proteomic studies, cancer, duplicate studies, in vitro studies, and evaluation of included studies. All included investigations were evaluated for biases. Results: Of 253 studies found, 29 were included. The extracts of Morus alba leaves at the phytochemical level improve glucose uptake. Chlorogenic acid, isoquercitrin, and quercitrin, present in the leaves of Morus alba, have hypoglycemic properties and an ameliorating effect on diabetic nephropathy. This leaf has pharmacological effects such as glucose absorption, insulin secretion production, antioxidant and anti-inflammatory agent, antihyperglycemic and antihyperlipidemic activities, and obesity management. Conclusions: Morus alba leaves have pharmacological effects on DM2 that include glucose absorption, production of insulin secretion, antioxidant agent, antihyperglycemic and antihyperlipidemic activities, and obesity control. Beyond these results, there is a lack of studies on the potential and synergistic effects of Morus alba leaves' components, limiting the possibility of a more effective therapy using the plant's leaves.
Objetivo: Analizar la producción científica en Scopus de las instituciones de salud nivel III en la Región La Libertad en Perú durante el periodo 2010 – 2019. Material y Métodos: Se realizó un análisis bibliométrico de la producción científica de las instituciones sanitarias del tercer nivel de atención de la Región La Libertad en Perú durante los años 2010 – 2019 teniendo como fuente referencial la información de la base de datos bibliográfica Scopus. Fueron incluidos: Hospital Regional Docente de Trujillo (HRDT), Hospital Belén de Trujillo (HBT), Hospital Víctor Lazarte Echegaray (HVLE) y Hospital de Alta Complejidad Virgen de la Puerta (HACVP). Resultados: No se halló registro de filiación institucional del HBT. HRDT tuvo la mayor producción científica con 33 artículos, seguido de HVLE y HACVP con 6 y 5 publicaciones respectivamente. El área temática más frecuente fue medicina, de igual forma los artículos originales, según tipo de documento. Según el país de origen de las revistas en donde fueron publicados los manuscritos académicos, España, Perú y Chile, ocuparon los 3 primeros lugares con 10, 6 y 5 artículos científicos en forma respectiva. Conclusión: Según la filiación consignada por los autores durante el periodo de estudio, la producción científica de las instituciones de salud nivel III en la Región La Libertad es baja, siendo el HRDT el nosocomio con mayor cantidad de publicaciones académicas; sin embargo, existe una tendencia progresiva al alza.
In this study, researchers examined the meaning of obesity among marriage and family Therapists utilizing a qualitative methodological approach (phenomenology). A total of 15 MFTs engaged in semi-structured interviews and reflected on their epistemology regarding obesity and weight-related concerns among individuals, couples and families, in addition to reflecting on their level of preparation regarding working with obese clients in clinical treatment. This study illuminated three themes: 1. Being unhealthy, being overweight; 2. personal knowledge and self-perceptions; and 3. Lack of knowledge and confidence. In this study, authors discuss clinical implications as well as provide recommendations regarding obesity training for therapists.
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