Point-of-Care Ultrasonography (PoCUS) aims to include a fifth pillar (insonation) in the classical physical examination in order to obtain images to answer specific questions by the clinician at the patient's bedside, PoCUS allowing rapid identification of structural or functional abnormalities, enabling more accurate volume assessment, supporting diagnosis, as well as guiding procedures. In recent years, PoCUS is becoming a valuable tool in day-to-day clinical practice, adopted by health care professionals from various medical specialties, never replacing physical examination but improving patient and medical care and experience. Renal patients represent a wide range of diseases, which gives PoCUS a special role to work with as a valuable tool in different scenarios, not only for volume-related information but also for the assessment of a wide range of acute and chronic conditions, enhancing the sensitivity of conventional physical examination in nephrology. PoCUS in the hands of a nephrologist is a precision medicine tool.

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