Obesitas atau berat badan berlebih adalah suatu penyakit yang ditandai adanya penimbunan jaringan lemak secara berlebih di dalam tubuh yang dapat memicu risiko terjadinya penyakit lain seperti hipertensi, jantung, diabetes hingga kematian. Di Provinsi Nusa Tenggara Timur (NTT) sendiri memiliki prevelensi obesitas pada penduduk umur 18 tahun keatas yakni 10,3 %. Salah satu upaya untuk mencegah obesitas dapat dilakukan dengan memanfaatkan bahan alam di Indonesia antara lain daun katuk (Sauropus androgynus L Merr) karena mengandung triterpenoid yang mempunyai efek antiobesitas. Tujuan penelitian ini adalah mengalisis potensi senyawa triterpenoid sebagai terapi anti diabetes secara molekuler. Senyawa Triterpenoid (CID 451674) diunduh dari database PubChem dan diminimalisir energi dengan perangkat lunak PyRX, Protein Lipase Pancreas diunduh dari database PDB. Senyawa titerpenoid diinteraksikan dengan Protein Lipase Pancreas menggunakan Hex versi 8.0.0. Protein lipase pancreas berikatan dengan senyawa triterpenoid pada tumbuhan daun katuk (Sauropus androgynus (L) Merr) dapat menghambat kinerja enzim lipase pancreas. Lipase memiliki manfaat dalam pemecahan trigliserida menjadi asam lemak. Yang kemudian diabsorbsi oleh usus halus dan disimpan dalam bentuk sel adiposa, dengan menghambat lipase ini menjadi alternative strategi untuk mencegah obesitas.
Community service activities at SD Negeri Gembira, Sikka Regency are to create a reading corner in the library. The purpose of creating a reading corner is to increase students' interest and motivation to read, encourage better library management, and help students to be able to take advantage of free time by reading. The activity of making a reading corner is an effort made as an answer to the problems found in the learning process in the classroom, namely that there are still students who have not been able to manage smoothly even though they have been in class VI. The use of the reading corner is made to target specifically for class VI students but does not close the opportunity to all students of SD Negeri Gembira. A series of PkM activities have been carried out from August to November 2022. All components at SD Negeri Gembira strongly support the creation of a reading corner. Learners have shown progress in learning especially reading proficiency.
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