The oral agent miltefosine has demonstrated a >95% cure rate in Indian visceral leishmaniasis. We performed a large, placebo-controlled study of miltefosine therapy (2.5 mg/kg per day orally for 28 days) against cutaneous leishmaniasis in Colombia and Guatemala. In regions in Colombia where Leishmania vianna panamensis is common, the per-protocol cure rates for miltefosine and placebo were 91% (40 of 44 patients) and 38% (9 of 24). These values are similar to historic values for the antimony standard of care and placebo. In regions in Guatemala where L. v. braziliensis and L. mexicana mexicana are common, the per-protocol cure rates were 53% (20 of 38) for miltefosine and 21% (4 of 19) for placebo. The miltefosine rate was lower than historic antimony cure rates of >90%. Miltefosine was well tolerated. Miltefosine is a useful oral agent against cutaneous leishmaniasis due to L. v. panamensis in Colombia but not against leishmaniasis due to L. v. braziliensis in Guatemala.

RESUMO:O presente trabalho foi desenvolvido com o objetivo de conhecer os significados atribuídos a vivência de pacientes estomizados, descrever seus conhecimentos sobre o autocuidado e identificar a importância das orientações de enfermagem para a sua adaptação. Pesquisa com abordagem qualitativa, realizada com 10 sujeitos associados ao programa de acompanhamento ao portador de estomia em um Centro de Referência a Estomizados, em Teresina-PI. Os dados foram obtidos por meio de entrevista e submetidos à análise de conteúdo, da qual emergiram três categorias que abordaram as mudanças no modo de vida do portador de estomia, o conhecimento do estomizado sobre o autocuidado e a orientação no processo de adaptação do portador de estomia. Concluiu-se que a estomia significa alterações no modo de vida e que a atuação da enfermagem através de atividades educativas é indispensável para o desenvolvimento do autocuidado e adaptação dos estomizados. DESCRITORES:Estomia. Autocuidado. Adaptação psicológica. Enfermagem. THE OSTOMY PATIENT'S LIVING EXPERIENCE: A CONTRIBUTION TO NURSING CAREABSTRACT: This project was developed aiming to better understand the meanings attributed to ostomy patients' living experiences, to describe their knowledge of self-care, and to identify the importance of nursing guidelines in their adaptation. This research was qualitative in nature, performed with 10 subjects associated to the ostomy patient care program in a Reference Center for Ostomy Patients in Teresina, PI, Brazil. The data was collected through interviews and submitted to content analysis, from which three categories were obtained which outline the changes to the ostomized patient's way of life, their knowledge about self-care, and the orientation received in the adaptation process after an ostomy. We conclude that the ostomy procedure signifies lifestyle alterations and that nursing care through educational activities is indispensable to develop self-care and satisfactory ostomy adaptation. DESCRIPTORS:Ostomy. Self care. Adaptation psychological. Nursing. LA EXPERIENCIA DEL PACIENTE OSTOMIZADO: UNA CONTRIBUCIÓN A LA ATENCIÓN DE ENFERMERÍA RESUMEN:El presente estudio se hizo con el objetivo de conocer los significados que se atribuyen a la experiencia de los pacientes ostomizados, describir sus conocimientos sobre su propio cuidado y determinar la importancia de las orientaciones de la enfermería para su adaptación. Se trata de una investigación de carácter cualitativo, llevada a cabo con diez sujetos asociados al programa de atención a personas con ostomía en un Centro de Referencia para Pacientes Ostomizados, en la ciudad de Teresina-PI. Los datos recolectados por medio de entrevistas se examinaron según el análisis de contenido, dando lugar a tres categorías que abordan los cambios en el modo de vida de la persona con ostomía, el conocimiento del paciente ostomizado sobre su propio cuidado y la orientación sobre el proceso de adaptación de la persona con ostomía. Se concluyó que la ostomía significa un cambio en la forma de vida y ...

Abstract. The purpose of this study was to assess photodynamic antimicrobial chemotherapy (PACT) via irradiation, using a low power laser associated with a photosensitization dye, as an alternative to remove cariogenic microorganisms by drilling. Remaining dentinal samples in deep carious lesions on permanent molars (n = 26) were treated with 0.01% methylene blue dye and irradiated with a low power laser (InGaAIP -indium gallium aluminum phosphide; λ = 660 nm; 100 mW; 320 Jcm − 2 ; 90 s; 9J). Samples of dentin from the pulpal wall region were collected with a micropunch before and immediately after PACT and kept in a transport medium for microbiological analysis. Samples were cultured in plates of Brucella blood agar, Mitis Salivarius Bacitracin agar and Rogosa SL agar to determine the total viable bacteria, mutans streptococci and Lactobacillus spp. counts, respectively. After incubation, colony-forming units were counted and microbial reduction was calculated for each group of bacteria. PACT led to statistically significant reductions in mutans streptococci (1.38 log), Lactobacillus spp. (0.93 log), and total viable bacteria (0.91 log). This therapy may be an appropriate approach for the treatment of deep carious lesions using minimally invasive procedures. C 2011 Society of Photo-Optical Instrumentation Engineers (SPIE).

Patients should be aware of minimizing the intake of colored staining solutions when submitted to resin infiltration treatment of white spot lesions in esthetically compromised areas. SUMMARYPurpose: The aim of this study was to investigate the staining behavior of demineralized enamel infiltrated by low-viscosity resin.Methods and Materials: Bovine enamel/dentin cylindrical samples (3 3 2 mm) were assigned into four groups (n=45) according to the enamel treatment: sound enamel (control), demineralization + artificial saliva, demineralization + daily application of 0.05% NaF, demineralization + resin infiltration (Icon, DMG). Artificial white spot lesions were produced in groups with demineralization. After the treatments, color was assessed by spectrophotometry, using the CIE L*a*b* system. The specimens (n=15) were then immersed in deionized water, red wine, or coffee for 10 minutes daily for eight days. Color was measured again, and the specimens were repolished with sandpaper discs. The final color was assessed. Data were analyzed by two-way analysis of variance and Tukey tests (a=0.05). A paired t-test was used for comparison between staining and repolishing conditions.Results: There were significant differences for surface treatment and dye after staining and repolishing. Immersion in wine and coffee resulted in significantly increased color alteration (DE) compared with water (p=0.001). The resin-infiltrated group exhibited the highest staining values (p=0.001). The repolishing procedures resulted in significantly decreased color change.

Como citar este artigo: Vieira CPB, Furtado AS, Almeida PCD, Luz MHBA, Pereira AFM. Prevalência e caracterização de feridas crônicas em idosos assistidos na atenção básica. Rev baiana enferm. 2017;31(3):e17397.Objetivo: analisar a prevalência e a caracterização de feridas crônicas em idosos assistidos na atenção básica e descrever as características sociodemográficas e clínicas desses idosos. Método: pesquisa transversal com 339 idosos, realizada entre janeiro e maio de 2016. Resultados: 55,8% tinham de 60 a 70 anos, 67,3% eram mulheres, sem escolaridade (44%), casadas (51,9%) e com uma ou mais doenças (91,7%). A prevalência foi de 8% (IC 95% 5,0-10,9), sendo 5% lesões por pressão e 2,9% úlceras vasculogênicas. Verificou-se associação da ocorrência de ferida crônica com escolaridade (p=0,03) e escore do Mini-Exame do Estado Mental (p=0,000) e diferença estatística na média da idade entre os idosos com lesões e os que não apresentavam lesão (p=0,000). Conclusão: houve baixa prevalência de feridas crônicas na população estudada. A região sacral foi a mais atingida e 48,2% das lesões apresentavam tecido de granulação e tinham média de tempo de existência de três anos.