To the Editor: Legionnaires' disease is an often severe form of pneumonia that is typically acquired by susceptible persons (e.g., elderly persons and smokers) through inhalation of aerosols that contain legionella species. 1-4 A cluster of cases of this disease occurred in Vila Franca de Xira, Portugal, in 2014. 5 One of the first cases of disease in this cluster occurred in a 48-year-old man (Patient 1), a smoker, who had been employed since October 6, 2014, as a maintenance worker at an industrial cooling tower complex in Vila Franca de Xira that was subsequently found to be contaminated with Legionella pneumophila. 5 He returned to the home that he shared with is mother in Porto (approximately 300 km from Vila Franca de Xira) on October 11 and again on the evening of October 19 (Fig. 1). His symptoms began on October 14, and on October 19, he had severe respiratory symptoms, including an intense cough. During that night, his mother (Patient 2) took care of him until he was admitted to the hospital (Centro Hospitalar do Porto) approximately 8 hours later. On October 22, he was transferred to another hospital to receive extracorporeal membrane oxygenation. On October 27, Patient 2, who was a previously healthy 74-year-old woman, began to report fever, cough, and loss of appetite. She was admitted to the same hospital on November 3 with septic shock due to pneumonia, and she died on December 1. Patient 1 died on January 7, 2015. Urine specimens obtained from both patients showed positive results on testing for legionella
Background
The total incidence of invasive meningococcal disease (IMD) in Europe has been declining in recent years; however, a rising incidence due to serogroup W (MenW), predominantly sequence type 11 (ST-11), clonal complex 11 (cc11), was reported in some European countries.
Aim
The aim of this study was to compile the most recent laboratory surveillance data on MenW IMD from several European countries to assess recent trends in Europe.
Methods
In this observational, retrospective study, IMD surveillance data collected from 2013–17 by national reference laboratories and surveillance units from 13 European countries were analysed using descriptive statistics.
Results
The overall incidence of IMD has been stable during the study period. Incidence of MenW IMD per 100,000 population (2013: 0.03; 2014: 0.05; 2015: 0.08; 2016: 0.11; 2017: 0.11) and the proportion of this serogroup among all invasive cases (2013: 5% (116/2,216); 2014: 9% (161/1,761); 2015: 13% (271/2,074); 2016: 17% (388/2,222); 2017: 19% (393/2,112)) continuously increased. The most affected countries were England, the Netherlands, Switzerland and Sweden. MenW was more frequent in older age groups (≥ 45 years), while the proportion in children (< 15 years) was lower than in other age groups. Of the culture-confirmed MenW IMD cases, 80% (615/767) were caused by hypervirulent cc11.
Conclusion
During the years 2013–17, an increase in MenW IMD, mainly caused by MenW cc11, was observed in the majority of European countries. Given the unpredictable nature of meningococcal spread and the epidemiological potential of cc11, European countries may consider preventive strategies adapted to their contexts.
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